Intracerebral hemorrhage treatment


GCS, systolic blood pressure, intraventricular hemorrhage, bleeding volume, and past blood pressure control are the main factors affecting the critical care needs of patients with ICH. 1).


Based on the MIMIC-III database, Yi et al. firstly described the dissimilarities in survival probability, mortality, and neurological recovery among mainstream treatments for intracerebral hemorrhage; secondly, patient classification was determined by important clinical features; and outcome variations among treatment groups were compared. The 28-day, 90-day, and in-hospital mortality in the craniotomy group were significantly lower than minimally invasive surgery (MIS) and non-surgical group patients; and, the medium/long-term mortality in the MIS group was significantly lower than the non-surgical group. The craniotomy group positively correlated with short-term GCS recovery compared with the MIS group; no difference existed between the non-surgical and MIS groups. The craniotomy group's 90-day survival probability and short-term GCS recovery were superior to the other two treatments in the subgroups of first GCS 3-12; this tendency also presented in the MIS group over the non-surgical group. For milder patients (first GCS > 12), the three treatment regimens had a minimal effect on patient survival, but the non-surgical group showed an advantage in short-term GCS recovery. Craniotomy patients have lower mortality and a better short-term neurological recovery in an ICH population, especially in short-to-medium term mortality and short-term neurological recovery over MIS patients. In addition, surgical treatment is recommendable for patients with a GCS ≤ 12. 2).


Anticoagulation reversal, intensive blood pressure lowering, neurosurgery and access to critical care might all be beneficial in acute intracerebral hemorrhage (ICH) 3).


1)
Wu C, Pan X, Xu L, Lu Z, Wang Z, Xu L, Xu Y. Development of a risk prediction model for critical care needs in patients with intracerebral hemorrhage: a retrospective cohort. BMC Nurs. 2024 Oct 19;23(1):770. doi: 10.1186/s12912-024-02319-8. PMID: 39427213.
2)
Yi Y, Che W, Cao Y, Chen F, Liao J, Wang X, Lyu J. Prognostic data analysis of surgical treatments for intracerebral hemorrhage. Neurosurg Rev. 2022 Apr 19. doi: 10.1007/s10143-022-01785-5. Epub ahead of print. PMID: 35441246.
3)
Parry-Jones AR, Sammut-Powell C, Paroutoglou K, Birleson E, Rowland J, Lee S, Cecchini L, Massyn M, Emsley R, Bray B, Patel H. An intracerebral hemorrhage care bundle is associated with lower case-fatality. Ann Neurol. 2019 Jul 10. doi: 10.1002/ana.25546. [Epub ahead of print] PubMed PMID: 31291031.
  • intracerebral_hemorrhage_treatment.txt
  • Last modified: 2024/10/20 16:10
  • by 127.0.0.1