Zurich publications

1: Imbach LL, Baumann CR, Poryazova R, Geissler O, Brugger P, Sarnthein J, Mothersill I, Weller M, Oertel MF, Stieglitz LH. Anticonvulsive effect of anterior thalamic deep brain stimulation in super-refractory status epilepticus crucially depends on active stimulation zone-A single case observation. Seizure. 2019 Aug 28;71:286-288. doi: 10.1016/j.seizure.2019.08.015. [Epub ahead of print] PubMed PMID: 31493681.

2: Wirth B, Kunz S, Schwyzer HK, Flury M, Lenz M, Audigé L. Repair of Lafosse I subscapularis lesions brings no benefit in anterosuperior rotator cuff reconstruction. Knee Surg Sports Traumatol Arthrosc. 2019 Sep 3. doi: 10.1007/s00167-019-05681-2. [Epub ahead of print] PubMed PMID: 31482182.

3: Brand F, Förster A, Christians A, Bucher M, Thomé CM, Raab MS, Westphal M, Pietsch T, von Deimling A, Reifenberger G, Claus P, Hentschel B, Weller M, Weber RG. FOCAD loss impacts microtubule assembly, G2/M progression and patient survival in astrocytic gliomas. Acta Neuropathol. 2019 Aug 31. doi: 10.1007/s00401-019-02067-z. [Epub ahead of print] PubMed PMID: 31473790.

4: Serra C, Guida L, Staartjes VE, Krayenbühl N, Türe U. Historical controversies about the thalamus: from etymology to function. Neurosurg Focus. 2019 Sep 1;47(3):E13. doi: 10.3171/2019.6.FOCUS19331. PubMed PMID: 31473672.

5: Sze L, Tschopp O, Neidert MC, Bernays RL, Ghirlanda C, Zwimpfer C, Wiesli P, Schmid C. Corrigendum to Soluble delta-like 1 homolog decreases in patients with acromegaly following pituitary surgery: A potential mediator of adipogenesis suppression by growth hormone? Growth Hormone & IGF Research 45 (2019) 20-24. Growth Horm IGF Res. 2019 Aug 26. pii: S1096-6374(19)30039-5. doi: 10.1016/j.ghir.2019.08.002. [Epub ahead of print] PubMed PMID: 31466842.

6: Stienen MN, Bartek J Jr, Czabanka MA, Freyschlag CF, Kolias A, Krieg SM, Moojen W, Renovanz M, Sampron N, Adib SD, Schubert GA, Demetriades AK, Ringel F, Regli L, Schaller K, Meling TR. Response to: neurosurgical procedures performed during residency in Europe-preliminary numbers and time trends. Acta Neurochir (Wien). 2019 Aug 29. doi: 10.1007/s00701-019-04048-3. [Epub ahead of print] PubMed PMID: 31463709.

7: Jeszenszky D, Kaiser B, Meuli M, Fekete TF, Haschtmann D. Correction to: Surgical growth guidance with non-fused anchoring segments in early-onset scoliosis. Eur Spine J. 2019 Aug 28. doi: 10.1007/s00586-019-06125-8. [Epub ahead of print] PubMed PMID: 31463537.

8: Staartjes VE, Klukowska AM, Schröder ML. Association of maximum back and leg pain severity with objective functional impairment as assessed by five-repetition sit-to-stand testing: analysis of two prospective studies. Neurosurg Rev. 2019 Aug 26. doi: 10.1007/s10143-019-01168-3. [Epub ahead of print] PubMed PMID: 31451936.

9: Moenninghoff C, Pohl E, Deuschl C, Wrede K, Jabbarli R, Radbruch A, Sure U, Forsting M, Wanke I. Outcomes After Onyx Embolization as Primary Treatment for Cranial Dural Arteriovenous Fistula in the Past Decade. Acad Radiol. 2019 Aug 21. pii: S1076-6332(19)30370-8. doi: 10.1016/j.acra.2019.07.021. [Epub ahead of print] PubMed PMID: 31445824.

10: Velz J, Bellut D, Krayenbühl N, Winklhofer S, Rushing E, Frauenknecht K. 69-year-old male with an intradural, extramedullary mass at T12-L1. Brain Pathol. 2019 Sep;29(5):693-694. doi: 10.1111/bpa.12765. PubMed PMID: 31441176.

11: Galldiks N, Kocher M, Ceccon G, Werner JM, Brunn A, Deckert M, Pope WB, Soffietti R, Le Rhun E, Weller M, Tonn JC, Fink GR, Langen KJ. Imaging challenges of immunotherapy and targeted therapy in patients with brain metastases: Response, Progression, and Pseudoprogression. Neuro Oncol. 2019 Aug 22. pii: noz147. doi: 10.1093/neuonc/noz147. [Epub ahead of print] PubMed PMID: 31437274.

12: Moiraghi A, Prada F, Delaidelli A, Guatta R, May A, Bartoli A, Saini M, Perin A, Wälchli T, Momjian S, Bijlenga P, Schaller K, DiMeco F. Navigated Intraoperative 2-Dimensional Ultrasound in High-Grade Glioma Surgery: Impact on Extent of Resection and Patient Outcome. Oper Neurosurg (Hagerstown). 2019 Aug 21. pii: opz203. doi: 10.1093/ons/opz203. [Epub ahead of print] PubMed PMID: 31435672.

13: Staartjes VE, Klukowska AM, Sorba EL, Schröder ML. Conflicts of interest in randomized controlled trials reported in neurosurgical journals. J Neurosurg. 2019 Aug 16:1-10. doi: 10.3171/2019.5.JNS183560. [Epub ahead of print] Review. PubMed PMID: 31419788.

14: Beaud ML, Rouiller EM, Bloch J, Mir A, Schwab ME, Schmidlin E. Combined with anti-Nogo-A antibody treatment, BDNF did not compensate the extra deleterious motor effect caused by large size cervical cord hemisection in adult macaques. CNS Neurosci Ther. 2019 Aug 16. doi: 10.1111/cns.13213. [Epub ahead of print] PubMed PMID: 31418518.

15: Wirsching HG, Arora S, Zhang H, Szulzewsky F, Cimino PJ, Quéva C, Houghton AM, Glorioso JC, Weller M, Holland EC. Cooperation of oncolytic virotherapy with VEGF-neutralizing antibody treatment in IDH wildtype glioblastoma dependends on MMP9. Neuro Oncol. 2019 Aug 15. pii: noz145. doi: 10.1093/neuonc/noz145. [Epub ahead of print] PubMed PMID: 31412117.

16: Gangkofner DS, Holzinger D, Schroeder L, Eichmüller SB, Zörnig I, Jäger D, Wichmann G, Dietz A, Broglie MA, Herold-Mende C, Dyckhoff G, Boscolo-Rizzo P, Ezic J, Marienfeld RB, Möller P, Völkel G, Kraus JM, Kestler HA, Brunner C, Schuler PJ, Wigand M, Theodoraki MN, Doescher J, Hoffmann TK, Pawlita M, Butt J, Waterboer T, Laban S. Patterns of antibody responses to nonviral cancer antigens in head and neck squamous cell carcinoma patients differ by human papillomavirus status. Int J Cancer. 2019 Aug 12. doi: 10.1002/ijc.32623. [Epub ahead of print] PubMed PMID: 31407331.

17: Hoogmoed J, de Oliveira Manoel AL, Coert BA, Marotta TR, Macdonald RL, Vandertop WP, Verbaan D, Germans MR. Why Do Patients with Poor-Grade Subarachnoid Hemorrhage Die? World Neurosurg. 2019 Aug 6. pii: S1878-8750(19)32137-0. doi: 10.1016/j.wneu.2019.07.221. [Epub ahead of print] PubMed PMID: 31398522.

18: Staartjes VE, Serra C, Maldaner N, Muscas G, Tschopp O, Soyka MB, Holzmann D, Regli L. The Zurich Pituitary Score predicts utility of intraoperative high-field magnetic resonance imaging in transsphenoidal pituitary neuroendocrine tumor surgery. Acta Neurochir (Wien). 2019 Aug 7. doi: 10.1007/s00701-019-04018-9. [Epub ahead of print] PubMed PMID: 31392567.

19: Okuchi S, Rojas-Garcia A, Ulyte A, Lopez I, Ušinskienė J, Lewis M, Hassanein SM, Sanverdi E, Golay X, Thust S, Panovska-Griffiths J, Bisdas S. Diagnostic accuracy of dynamic contrast-enhanced perfusion MRI in stratifying gliomas: A systematic review and meta-analysis. Cancer Med. 2019 Aug 7. doi: 10.1002/cam4.2369. [Epub ahead of print] PubMed PMID: 31389669.

20: Brown TJ, Bota DA, van Den Bent MJ, Brown PD, Maher E, Aregawi D, Liau LM, Buckner JC, Weller M, Berger MS, Glantz M. Management of low-grade glioma: a systematic review and meta-analysis. Neurooncol Pract. 2019 Jul;6(4):249-258. doi: 10.1093/nop/npy034. Epub 2018 Aug 18. Review. PubMed PMID: 31386075; PubMed Central PMCID: PMC6660818.

21: Eisele G, Roelcke U, Conen K, Huber F, Weiss T, Hofer S, Heese O, Westphal M, Hertler C, Roth P, Weller M. Complementary and alternative medicine use by glioma patients in Switzerland. Neurooncol Pract. 2019 May;6(3):237-244. doi: 10.1093/nop/npy035. Epub 2018 Oct 12. PubMed PMID: 31386047; PubMed Central PMCID: PMC6656325.

22: Henzi S, Krayenbühl N, Bozinov O, Regli L, Stienen MN. Ultrasonic aspiration in neurosurgery: comparative analysis of complications and outcome for three commonly used models. Acta Neurochir (Wien). 2019 Aug 3. doi: 10.1007/s00701-019-04021-0. [Epub ahead of print] PubMed PMID: 31377957.

23: Aloia A, Müllhaupt D, Chabbert CD, Eberhart T, Flueckiger S, Vukolic A, Eichhoff OM, Irmisch A, Alexander LT, Scibona E, Frederick DT, Miao B, Tian T, Cheng C, Kwong LN, Wei Z, Sullivan RJ, Boland GM, Herlyn M, Flaherty KT, Zamboni N, Dummer R, Zhang G, Levesque MP, Krek W, Kovacs WJ. A fatty acid oxidation-dependent metabolic shift regulates the adaptation of BRAF-mutated melanoma to MAPK inhibitors. Clin Cancer Res. 2019 Aug 2. pii: clincanres.0253.2019. doi: 10.1158/1078-0432.CCR-19-0253. [Epub ahead of print] PubMed PMID: 31375515.

24: Dias SF, Lalou AD, Spang R, Haas-Lude K, Garnett M, Fernandez H, Czosnyka M, Schuhmann MU, Czosnyka Z. Value of computerized shunt infusion study in assessment of pediatric hydrocephalus shunt function-a two center cross-sectional study. Childs Nerv Syst. 2019 Aug 1. doi: 10.1007/s00381-019-04264-3. [Epub ahead of print] PubMed PMID: 31372736.

25: Haemmerli J, Lenga P, Hong B, Kursumovic A, Maldaner N, Burkhardt JK, Bijlenga P, Rüfenacht DA, Schmidt NO, Vajkoczy P, Dengler J. Clinical implications and radiographic characteristics of the relation between giant intracranial aneurysms of the posterior circulation and the brainstem. Acta Neurochir (Wien). 2019 Sep;161(9):1747-1753. doi: 10.1007/s00701-019-04016-x. Epub 2019 Jul 29. PubMed PMID: 31359190.

26: Hubli M, Kramer JLK, Jutzeler CR, Rosner J, Furlan JC, Tansey KE, Schubert M. Application of electrophysiological measures in spinal cord injury clinical trials: a narrative review. Spinal Cord. 2019 Jul 23. doi: 10.1038/s41393-019-0331-z. [Epub ahead of print] Review. PubMed PMID: 31337870.

27: Stienen MN, Geisseler O, Velz J, Maldaner N, Sebök M, Dannecker N, Rothacher Y, Schlosser L, Smoll NR, Keller E, Brugger P, Regli L. Influence of the Intensive Care Unit Environment on the Reliability of the Montreal Cognitive Assessment. Front Neurol. 2019 Jul 3;10:734. doi: 10.3389/fneur.2019.00734. eCollection 2019. PubMed PMID: 31333576; PubMed Central PMCID: PMC6617738.

28: Ames CP, Smith JS, Pellisé F, Kelly M, Gum JL, Alanay A, Acaroğlu E, Pérez-Grueso FJS, Kleinstück FS, Obeid I, Vila-Casademunt A, Shaffrey CI Jr, Burton DC, Lafage V, Schwab FJ, Shaffrey CI Sr, Bess S, Serra-Burriel M; European Spine Study Group; International Spine Study Group. Development of predictive models for all individual questions of SRS-22R after adult spinal deformity surgery: a step toward individualized medicine. Eur Spine J. 2019 Sep;28(9):1998-2011. doi: 10.1007/s00586-019-06079-x. Epub 2019 Jul 19. PubMed PMID: 31325052.

29: Voormolen EH, Diederen S, Cebula H, Woerdeman PA, Noordmans HJ, Viergever MA, Robe PA, Froelich S, Regli L, Berkelbach van der Sprenkel JW. Distance Control and Virtual Drilling Improves Anatomical Orientation During Anterior Petrosectomy. Oper Neurosurg (Hagerstown). 2019 Apr 24. pii: opz064. doi: 10.1093/ons/opz064. [Epub ahead of print] PubMed PMID: 31323686.

30: Weller M, Le Rhun E, Preusser M, Tonn JC, Roth P. How we treat glioblastoma. ESMO Open. 2019 Jun 17;4(Suppl 2):e000520. doi: 10.1136/esmoopen-2019-000520. eCollection 2019. Review. PubMed PMID: 31297242; PubMed Central PMCID: PMC6586206.

31: Wirsching HG, Zhang H, Szulzewsky F, Arora S, Grandi P, Cimino PJ, Amankulor N, Campbell JS, McFerrin L, Pattwell SS, Ene C, Hicks A, Ball M, Yan J, Zhang J, Kumasaka D, Pierce RH, Weller M, Finer M, Quéva C, Glorioso JC, Houghton AM, Holland EC. Arming oHSV with ULBP3 drives abscopal immunity in lymphocyte-depleted glioblastoma. JCI Insight. 2019 Jul 11;4(13). pii: 128217. doi: 10.1172/jci.insight.128217. eCollection 2019 Jul 11. PubMed PMID: 31292299; PubMed Central PMCID: PMC6629248.

32: Muroi C, Meier S, De Luca V, Mack DJ, Strässle C, Schwab P, Karlen W, Keller E. Automated False Alarm Reduction in a Real-Life Intensive Care Setting Using Motion Detection. Neurocrit Care. 2019 Jul 9. doi: 10.1007/s12028-019-00711-w. [Epub ahead of print] PubMed PMID: 31290067.

33: Muhammad S, Tanikawa R, Lawton M, Regli L, Niemelä M, Korja M. Microsurgical dissection of Sylvian fissure-short technical videos of third generation cerebrovascular neurosurgeons. Acta Neurochir (Wien). 2019 Sep;161(9):1743-1746. doi: 10.1007/s00701-019-03999-x. Epub 2019 Jul 8. PubMed PMID: 31281944; PubMed Central PMCID: PMC6704088.

34: Levin J, Maaß S, Schuberth M, Giese A, Oertel WH, Poewe W, Trenkwalder C, Wenning GK, Mansmann U, Südmeyer M, Eggert K, Mollenhauer B, Lipp A, Löhle M, Classen J, Münchau A, Kassubek J, Gandor F, Berg D, Egert-Schwender S, Eberhardt C, Paul F, Bötzel K, Ertl-Wagner B, Huppertz HJ, Ricard I, Höglinger GU; PROMESA Study Group. Safety and efficacy of epigallocatechin gallate in multiple system atrophy (PROMESA): a randomised, double-blind, placebo-controlled trial. Lancet Neurol. 2019 Aug;18(8):724-735. doi: 10.1016/S1474-4422(19)30141-3. Epub 2019 Jul 2. PubMed PMID: 31278067.

35: Baltsavias G, Valavanis A, Regli L. Cranial dural arteriovenous shunts: selection of the ideal lesion for surgical occlusion according to the classification system. Acta Neurochir (Wien). 2019 Sep;161(9):1775-1781. doi: 10.1007/s00701-019-03984-4. Epub 2019 Jul 3. PubMed PMID: 31267189.

36: Detmer FJ, Hadad S, Chung BJ, Mut F, Slawski M, Juchler N, Kurtcuoglu V, Hirsch S, Bijlenga P, Uchiyama Y, Fujimura S, Yamamoto M, Murayama Y, Takao H, Koivisto T, Frösen J, Cebral JR. Extending statistical learning for aneurysm rupture assessment to Finnish and Japanese populations using morphology, hemodynamics, and patient characteristics. Neurosurg Focus. 2019 Jul 1;47(1):E16. doi: 10.3171/2019.4.FOCUS19145. PubMed PMID: 31261120.

37: Pellisé F, Serra-Burriel M, Smith JS, Haddad S, Kelly MP, Vila-Casademunt A, Sánchez Pérez-Grueso FJ, Bess S, Gum JL, Burton DC, Acaroğlu E, Kleinstück F, Lafage V, Obeid I, Schwab F, Shaffrey CI, Alanay A, Ames C; International Spine Study Group; European Spine Study Group. Development and validation of risk stratification models for adult spinal deformity surgery. J Neurosurg Spine. 2019 Jun 28:1-13. doi: 10.3171/2019.3.SPINE181452. [Epub ahead of print] PubMed PMID: 31252385.

38: Sievers P, Appay R, Schrimpf D, Stichel D, Reuss DE, Wefers AK, Reinhardt A, Coras R, Ruf VC, Schmid S, de Stricker K, Boldt HB, Kristensen BW, Petersen JK, Ulhøi BP, Gardberg M, Aronica E, Hasselblatt M, Brück W, Bielle F, Mokhtari K, Lhermitte B, Wick W, Herold-Mende C, Hänggi D, Brandner S, Giangaspero F, Capper D, Rushing E, Wesseling P, Pfister SM, Figarella-Branger D, von Deimling A, Sahm F, Jones DTW. Rosette-forming glioneuronal tumors share a distinct DNA methylation profile and mutations in FGFR1, with recurrent co-mutation of PIK3CA and NF1. Acta Neuropathol. 2019 Sep;138(3):497-504. doi: 10.1007/s00401-019-02038-4. Epub 2019 Jun 27. PubMed PMID: 31250151.

39: Audigé L, Graf L, Flury M, Schneider MM, Müller AM. Functional improvement is sustained following anatomical and reverse shoulder arthroplasty for fracture sequelae: a registry-based analysis. Arch Orthop Trauma Surg. 2019 Jun 24. doi: 10.1007/s00402-019-03224-5. [Epub ahead of print] PubMed PMID: 31236674.

40: Le Rhun E, Preusser M, van den Bent M, Andratschke N, Weller M. How we treat patients with leptomeningeal metastases. ESMO Open. 2019 May 21;4(Suppl 2):e000507. doi: 10.1136/esmoopen-2019-000507. eCollection 2019. Review. PubMed PMID: 31231573; PubMed Central PMCID: PMC6555600.

41: Staartjes VE, Zattra CM, Akeret K, Maldaner N, Muscas G, Bas van Niftrik CH, Fierstra J, Regli L, Serra C. Neural network-based identification of patients at high risk for intraoperative cerebrospinal fluid leaks in endoscopic pituitary surgery. J Neurosurg. 2019 Jun 21:1-7. doi: 10.3171/2019.4.JNS19477. [Epub ahead of print] PubMed PMID: 31226693.

42: di Giacopo A, Baumann CR, Kurthen M, Capecchi F, Sürücü O, Imbach LL. Selective deep brain stimulation in the substantia nigra reduces myoclonus in progressive myoclonic epilepsy: a novel observation and short review of the literature. Epileptic Disord. 2019 Jun 1;21(3):283-288. doi: 10.1684/epd.2019.1072. PubMed PMID: 31225807.

43: Louis DN, Wesseling P, Brandner S, Brat DJ, Ellison DW, Giangaspero F, Hattab EM, Hawkins C, Judge MJ, Kleinschmidt-DeMasters B, Komori T, McLean C, Paulus W, Perry A, Reifenberger G, Weller M, Rous B. Data Sets for the Reporting of Tumors of the Central Nervous System. Arch Pathol Lab Med. 2019 Jun 20. doi: 10.5858/arpa.2018-0565-OA. [Epub ahead of print] PubMed PMID: 31219344.

44: Ames CP, Smith JS, Pellisé F, Kelly M, Alanay A, Acaroğlu E, Pérez-Grueso FJS, Kleinstück F, Obeid I, Vila-Casademunt A, Shaffrey CI Jr, Burton D, Lafage V, Schwab F, Shaffrey CI Sr, Bess S, Serra-Burriel M; European Spine Study Group, International Spine Study Group. Artificial Intelligence Based Hierarchical Clustering of Patient Types and Intervention Categories in Adult Spinal Deformity Surgery: Towards a New Classification Scheme that Predicts Quality and Value. Spine (Phila Pa 1976). 2019 Jul 1;44(13):915-926. doi: 10.1097/BRS.0000000000002974. PubMed PMID: 31205167.

45: Fregosi M, Contestabile A, Badoud S, Borgognon S, Cottet J, Brunet JF, Bloch J, Schwab ME, Rouiller EM. Corticotectal Projections From the Premotor or Primary Motor Cortex After Cortical Lesion or Parkinsonian Symptoms in Adult Macaque Monkeys: A Pilot Tracing Study. Front Neuroanat. 2019 May 22;13:50. doi: 10.3389/fnana.2019.00050. eCollection 2019. PubMed PMID: 31191260; PubMed Central PMCID: PMC6540615.

46: Padevit L, Sarnthein J, Stienen MN, Krayenbühl N, Bozinov O, Regli L, Neidert MC. Smoking status and perioperative adverse events in patients undergoing cranial tumor surgery. J Neurooncol. 2019 Aug;144(1):97-105. doi: 10.1007/s11060-019-03206-y. Epub 2019 Jun 11. PubMed PMID: 31183602.

47: Aimetti AA, Kirshblum S, Curt A, Mobley J, Grossman RG, Guest JD. Natural history of neurological improvement following complete (AIS A) thoracic spinal cord injury across three registries to guide acute clinical trial design and interpretation. Spinal Cord. 2019 Sep;57(9):753-762. doi: 10.1038/s41393-019-0299-8. Epub 2019 Jun 10. PubMed PMID: 31182786.

48: Nassiri F, Mamatjan Y, Suppiah S, Badhiwala JH, Mansouri S, Karimi S, Saarela O, Poisson L, Gepfner-Tuma I, Schittenhelm J, Ng HK, Noushmehr H, Harter P, Baumgarten P, Weller M, Preusser M, Herold-Mende C, Tatagiba M, Tabatabai G, Sahm F, von Deimling A, Zadeh G, Aldape KD; International Consortium on Meningiomas . DNA methylation profiling to predict recurrence risk in meningioma: development and validation of a nomogram to optimize clinical management. Neuro Oncol. 2019 Jun 3. pii: noz061. doi: 10.1093/neuonc/noz061. [Epub ahead of print] PubMed PMID: 31158293; PubMed Central PMCID: PMC6620635.

49: Gallay MN, Moser D, Federau C, Jeanmonod D. Radiological and Thermal Dose Correlations in Pallidothalamic Tractotomy With MRgFUS. Front Surg. 2019 May 17;6:28. doi: 10.3389/fsurg.2019.00028. eCollection 2019. PubMed PMID: 31157233; PubMed Central PMCID: PMC6533852.

50: Davies BM, Khan DZ, Mowforth OD, McNair AGK, Gronlund T, Kolias AG, Tetreault L, Starkey ML, Sadler I, Sarewitz E, Houlton D, Carter J, Kalsi-Ryan S, Aarabi B, Kwon BK, Kurpad SN, Harrop J, Wilson JR, Grossman R, Curt A, Fehlings MG, Kotter MRN. RE-CODE DCM (REsearch Objectives and Common Data Elements for Degenerative Cervical Myelopathy): A Consensus Process to Improve Research Efficiency in DCM, Through Establishment of a Standardized Dataset for Clinical Research and the Definition of the Research Priorities. Global Spine J. 2019 May;9(1 Suppl):65S-76S. doi: 10.1177/2192568219832855. Epub 2019 May 8. PubMed PMID: 31157148; PubMed Central PMCID: PMC6512197.

51: van Niftrik CHB, van der Wouden F, Staartjes VE, Fierstra J, Stienen MN, Akeret K, Sebök M, Fedele T, Sarnthein J, Bozinov O, Krayenbühl N, Regli L, Serra C. Machine Learning Algorithm Identifies Patients at High Risk for Early Complications After Intracranial Tumor Surgery: Registry-Based Cohort Study. Neurosurgery. 2019 May 31. pii: nyz145. doi: 10.1093/neuros/nyz145. [Epub ahead of print] PubMed PMID: 31149726.

52: Zarb Y, Franzoso FD, Keller A. Pericytes in Primary Familial Brain Calcification. Adv Exp Med Biol. 2019;1147:247-264. doi: 10.1007/978-3-030-16908-4_11. Review. PubMed PMID: 31147881.

53: Chou SH, Macdonald RL, Keller E; Unruptured Intracranial Aneurysms and SAH CDE Project Investigators. Biospecimens and Molecular and Cellular Biomarkers in Aneurysmal Subarachnoid Hemorrhage Studies: Common Data Elements and Standard Reporting Recommendations. Neurocrit Care. 2019 Jun;30(Suppl 1):46-59. doi: 10.1007/s12028-019-00725-4. PubMed PMID: 31144274.

54: Hejrati N, Spieler D, Samuel R, Regli L, Weyerbrock A, Surbeck W. Conscious Experience and Psychological Consequences of Awake Craniotomy. World Neurosurg. 2019 Sep;129:e381-e386. doi: 10.1016/j.wneu.2019.05.156. Epub 2019 May 25. PubMed PMID: 31136840.

55: Roder C, Hauser TK, Ernemann U, Tatagiba M, Khan N, Bender B. Arterial wall contrast enhancement in progressive moyamoya disease. J Neurosurg. 2019 May 24:1-9. doi: 10.3171/2019.2.JNS19106. [Epub ahead of print] PubMed PMID: 31125967.

56: Maldaner N, Sosnova M, Sarnthein J, Bozinov O, Regli L, Stienen MN. Predicting Functional Impairment in patients with chronic subdural hematoma treated with burr hole Trepanation-The FIT-score. Clin Neurol Neurosurg. 2019 Jul;182:142-147. doi: 10.1016/j.clineuro.2019.05.012. Epub 2019 May 14. PubMed PMID: 31125897.

57: Schröder ML, de Wispelaere MP, Staartjes VE. Predictors of loss of follow-up in a prospective registry: which patients drop out 12 months after lumbar spine surgery? Spine J. 2019 May 21. pii: S1529-9430(19)30188-3. doi: 10.1016/j.spinee.2019.05.007. [Epub ahead of print] PubMed PMID: 31125698.

58: Stienen MN, Visser-Meily JM, Schweizer TA, Hänggi D, Macdonald RL, Vergouwen MDI; Unruptured Intracranial Aneurysms and SAH CDE Project Investigators. Prioritization and Timing of Outcomes and Endpoints After Aneurysmal Subarachnoid Hemorrhage in Clinical Trials and Observational Studies: Proposal of a Multidisciplinary Research Group. Neurocrit Care. 2019 Jun;30(Suppl 1):102-113. doi: 10.1007/s12028-019-00737-0. PubMed PMID: 31123994.

59: Hackenberg KAM, Etminan N, Wintermark M, Meyers PM, Lanzino G, Rüfenacht D, Krings T, Huston J 3rd, Rinkel G, Derdeyn C; Unruptured Intracranial Aneurysms and SAH CDE Project Investigators. Common Data Elements for Radiological Imaging of Patients with Subarachnoid Hemorrhage: Proposal of a Multidisciplinary Research Group. Neurocrit Care. 2019 Jun;30(Suppl 1):60-78. doi: 10.1007/s12028-019-00728-1. PubMed PMID: 31115823.

60: Flippot R, Biondani P, Auclin E, Xiao D, Hendriks L, Le Rhun E, Leduc C, Beau-Faller M, Gervais R, Remon J, Adam J, Planchard D, Lavaud P, Naltet C, Caramella C, Le Pechoux C, Lacroix L, Gazzah A, Mezquita L, Besse B. Activity of EGFR Tyrosine Kinase Inhibitors in NSCLC With Refractory Leptomeningeal Metastases. J Thorac Oncol. 2019 Aug;14(8):1400-1407. doi: 10.1016/j.jtho.2019.05.007. Epub 2019 May 18. PubMed PMID: 31108248.

61: Dias SF, Jehli E, Regli L, Sarnthein J, Germans MR. Multimodal Monitoring Strategy Is Decisive in Elective Middle Cerebral Artery Aneurysm Clipping: A Case Report. World Neurosurg. 2019 Feb;122:43-47. doi: 10.1016/j.wneu.2018.10.096. Epub 2018 Oct 25. PubMed PMID: 31108065.

62: Bucher B, Maldaner N, Regli L, Sarnthein J, Serra C. Standardized assessment of outcome and complications in chronic subdural hematoma: results from a large case series. Acta Neurochir (Wien). 2019 Jul;161(7):1297-1304. doi: 10.1007/s00701-019-03884-7. Epub 2019 May 20. PubMed PMID: 31106394.

63: Zipser CM, Deuel J, Ernst J, Schubert M, von Känel R, Böttger S. The predisposing and precipitating risk factors for delirium in neurosurgery: a prospective cohort study of 949 patients. Acta Neurochir (Wien). 2019 Jul;161(7):1307-1315. doi: 10.1007/s00701-019-03927-z. Epub 2019 May 20. PubMed PMID: 31106393.

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66: Nowosielski M, Gorlia T, Bromberg JEC, Sahm F, Harting I, Kickingereder P, Brandes AA, Taphoorn MJB, Taal W, Domont J, Idbaih A, Campone M, Clement PM, Weller M, Fabbro M, Le Rhun E, Platten M, Golfinopoulos V, van den Bent MJ, Bendszus M, Wick W. Imaging necrosis during treatment is associated with worse survival in EORTC 26101 study. Neurology. 2019 Jun 11;92(24):e2754-e2763. doi: 10.1212/WNL.0000000000007643. Epub 2019 May 10. PubMed PMID: 31076534.

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69: Wirthschaft P, Bode J, Soni H, Dietrich F, Krüwel T, Fischer B, Knobbe-Thomsen CB, Rossetti G, Hentschel A, Mack N, Schönig K, Breckwoldt MO, Schmandke A, Pusch S, Medenbach J, Bendszus M, Schwab ME, von Deimling A, Kool M, Herold-Mende C, Reifenberger G, Ahrends R, Tews B. RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas. Acta Neuropathol. 2019 Aug;138(2):275-293. doi: 10.1007/s00401-019-02021-z. Epub 2019 May 6. PubMed PMID: 31062076; PubMed Central PMCID: PMC6660512.

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72: Perez FA, Quinet S, Jarvik JG, Nguyen QT, Aghayev E, Jitjai D, Hwang WD, Jarvik ER, Nedeljkovic SS, Avins AL, Schwalb JM, Diehn FE, Standaert CJ, Nerenz DR, Annaswamy T, Bauer Z, Haynor D, Heagerty PJ, Friedly JL. Lumbar Spinal Stenosis Severity by CT or MRI Does Not Predict Response to Epidural Corticosteroid versus Lidocaine Injections. AJNR Am J Neuroradiol. 2019 May;40(5):908-915. doi: 10.3174/ajnr.A6050. Epub 2019 May 2. PubMed PMID: 31048295.

73: Stienen MN, Maldaner N, Joswig H, Corniola MV, Bellut D, Prömmel P, Regli L, Weyerbrock A, Schaller K, Gautschi OP. Objective functional assessment using the “Timed Up and Go” test in patients with lumbar spinal stenosis. Neurosurg Focus. 2019 May 1;46(5):E4. doi: 10.3171/2019.2.FOCUS18618. PubMed PMID: 31042663.

74: Siccoli A, de Wispelaere MP, Schröder ML, Staartjes VE. Machine learning-based preoperative predictive analytics for lumbar spinal stenosis. Neurosurg Focus. 2019 May 1;46(5):E5. doi: 10.3171/2019.2.FOCUS18723. PubMed PMID: 31042660.

75: Rubio-Gozalbo ME, Haskovic M, Bosch AM, Burnyte B, Coelho AI, Cassiman D, Couce ML, Dawson C, Demirbas D, Derks T, Eyskens F, Forga MT, Grunewald S, Häberle J, Hochuli M, Hubert A, Huidekoper HH, Janeiro P, Kotzka J, Knerr I, Labrune P, Landau YE, Langendonk JG, Möslinger D, Müller-Wieland D, Murphy E, Õunap K, Ramadza D, Rivera IA, Scholl-Buergi S, Stepien KM, Thijs A, Tran C, Vara R, Visser G, Vos R, de Vries M, Waisbren SE, Welsink-Karssies MM, Wortmann SB, Gautschi M, Treacy EP, Berry GT. The natural history of classic galactosemia: lessons from the GalNet registry. Orphanet J Rare Dis. 2019 Apr 27;14(1):86. doi: 10.1186/s13023-019-1047-z. PubMed PMID: 31029175; PubMed Central PMCID: PMC6486996.

76: Ulrich NH, Burgstaller JM, Gravestock I, Pichierri G, Wertli MM, Steurer J, Farshad M, Porchet F. Outcome of unilateral versus standard open midline approach for bilateral decompression in lumbar spinal stenosis: is “over the top” really better? A Swiss prospective multicenter cohort study. J Neurosurg Spine. 2019 Apr 26:1-10. doi: 10.3171/2019.2.SPINE181309. [Epub ahead of print] PubMed PMID: 31026821.

77: Starnoni D, Maduri R, Al Taha K, Bervini D, Zumofen DW, Stienen MN, Schatlo B, Fung C, Robert T, Seule MA, Burkhardt JK, Maldaner N, Rothlisberger M, Blackham KA, Marbacher S, D'Alonzo D, Remonda L, Machi P, Gralla J, Bijlenga P, Saliou G, Ballabeni P, Levivier M, Messerer M; Swiss SOS Group, Daniel RT. Ruptured PICA aneurysms: presentation and treatment outcomes compared to other posterior circulation aneurysms. A Swiss SOS study. Acta Neurochir (Wien). 2019 Jul;161(7):1325-1334. doi: 10.1007/s00701-019-03894-5. Epub 2019 Apr 26. Erratum in: Acta Neurochir (Wien). 2019 May 17;:. PubMed PMID: 31025178.

78: Binder H, Willscher E, Loeffler-Wirth H, Hopp L, Jones DTW, Pfister SM, Kreuz M, Gramatzki D, Fortenbacher E, Hentschel B, Tatagiba M, Herrlinger U, Vatter H, Matschke J, Westphal M, Krex D, Schackert G, Tonn JC, Schlegel U, Steiger HJ, Wick W, Weber RG, Weller M, Loeffler M. DNA methylation, transcriptome and genetic copy number signatures of diffuse cerebral WHO grade II/III gliomas resolve cancer heterogeneity and development. Acta Neuropathol Commun. 2019 Apr 25;7(1):59. doi: 10.1186/s40478-019-0704-8. PubMed PMID: 31023364; PubMed Central PMCID: PMC6482573.

79: Kugathasan U, Evans MRB, Morrow JM, Sinclair CDJ, Thornton JS, Yousry TA, Hornemann T, Suriyanarayanan S, Owusu-Ansah K, Lauria G, Lombardi R, Polke JM, Wilson E, Bennett DLH, Houlden H, Hanna MG, Blake JC, Laura M, Reilly MM. Development of MRC Centre MRI calf muscle fat fraction protocol as a sensitive outcome measure in Hereditary Sensory Neuropathy Type 1. J Neurol Neurosurg Psychiatry. 2019 Aug;90(8):895-906. doi: 10.1136/jnnp-2018-320198. Epub 2019 Apr 17. PubMed PMID: 30995999.

80: Zhao YH, Wang ZF, Pan ZY, Péus D, Delgado-Fernandez J, Pallud J, Li ZQ. A Meta-Analysis of Survival Outcomes Following Reoperation in Recurrent Glioblastoma: Time to Consider the Timing of Reoperation. Front Neurol. 2019 Mar 26;10:286. doi: 10.3389/fneur.2019.00286. eCollection 2019. PubMed PMID: 30984099; PubMed Central PMCID: PMC6448034.

81: Salamanca L, Mechawar N, Murai KK, Balling R, Bouvier DS, Skupin A. MIC-MAC: An automated pipeline for high-throughput characterization and classification of three-dimensional microglia morphologies in mouse and human postmortem brain samples. Glia. 2019 Aug;67(8):1496-1509. doi: 10.1002/glia.23623. Epub 2019 Apr 14. PubMed PMID: 30983036; PubMed Central PMCID: PMC6617786.

82: Blight AR, Hsieh J, Curt A, Fawcett JW, Guest JD, Kleitman N, Kurpad SN, Kwon BK, Lammertse DP, Weidner N, Steeves JD. The challenge of recruitment for neurotherapeutic clinical trials in spinal cord injury. Spinal Cord. 2019 May;57(5):348-359. doi: 10.1038/s41393-019-0276-2. Epub 2019 Apr 8. Review. PubMed PMID: 30962518.

83: Siccoli A, Klukowska AM, Schröder ML, Staartjes VE. A Systematic Review and Meta-Analysis of Perioperative Parameters in Robot-Guided, Navigated, and Freehand Thoracolumbar Pedicle Screw Instrumentation. World Neurosurg. 2019 Jul;127:576-587.e5. doi: 10.1016/j.wneu.2019.03.196. Epub 2019 Apr 4. Review. PubMed PMID: 30954747.

84: Serra C, Staartjes VE, Maldaner N, Muscas G, Akeret K, Holzmann D, Soyka MB, Schmid C, Regli L. Response to “Going beyond scoring systems for cavernous sinus involvement in trans-sphenoidal pituitary surgery”. Acta Neurochir (Wien). 2019 May;161(5):1035-1036. doi: 10.1007/s00701-019-03891-8. Epub 2019 Apr 5. PubMed PMID: 30953155.

85: Macdonald RL, Katan M. Haptoglobin and hemoglobin in subarachnoid hemorrhage: A tale of 2 globins. Neurology. 2019 Apr 30;92(18):831-832. doi: 10.1212/WNL.0000000000007399. Epub 2019 Apr 5. PubMed PMID: 30952791.

86: Held U, Steurer J, Pichierri G, Wertli MM, Farshad M, Brunner F, Guggenberger R, Porchet F, Fekete TF, Schmid UD, Gravestock I, Burgstaller JM. What is the treatment effect of surgery compared with nonoperative treatment in patients with lumbar spinal stenosis at 1-year follow-up? J Neurosurg Spine. 2019 Apr 5:1-9. doi: 10.3171/2019.1.SPINE181098. [Epub ahead of print] PubMed PMID: 30952135.

87: Wang SS, Yang Y, Velz J, Keller E, Luft AR, Regli L, Neidert MC, Bozinov O. Management of brainstem haemorrhages. Swiss Med Wkly. 2019 Apr 5;149:w20062. doi: 10.4414/smw.2019.20062. eCollection 2019 Mar 25. PubMed PMID: 30950504.

88: Warner FM, Jutzeler CR, Cragg JJ, Tong B, Grassner L, Bradke F, Geisler F, Kramer JK. The Effect of Non-Gabapentinoid Anticonvulsants on Sensorimotor Recovery After Human Spinal Cord Injury. CNS Drugs. 2019 May;33(5):503-511. doi: 10.1007/s40263-019-00622-6. PubMed PMID: 30949923.

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90: Stienen MN, Bellut D, Stojanov D, Eriks-Hoogland I, Regli L, Oertel MF. [Reversible Paraplegia - Favorable Outcome After Delayed Diagnosis]. Praxis (Bern 1994). 2019;108(5):341-345. doi: 10.1024/1661-8157/a003205. German. PubMed PMID: 30940039.

91: Lachenmayer ML, Bettschen C, Bernasconi C, Petermann K, Debove I, Muellner J, Michelis JP, Burgunder JM, Krauss JK, Oertel MF, Pollo C, Kaelin-Lang A, Schüpbach M. Stimulation of the globus pallidus internus in the treatment of Parkinson's disease: Long-term results of a monocentric cohort. Parkinsonism Relat Disord. 2019 Mar 16. pii: S1353-8020(19)30102-6. doi: 10.1016/j.parkreldis.2019.03.009. [Epub ahead of print] PubMed PMID: 30935828.

92: Staartjes VE, de Wispelaere MP, Schröder ML. Improving recovery after elective degenerative spine surgery: 5-year experience with an enhanced recovery after surgery (ERAS) protocol. Neurosurg Focus. 2019 Apr 1;46(4):E7. doi: 10.3171/2019.1.FOCUS18646. PubMed PMID: 30933924.

93: Hainc N, Stippich C, Reinhardt J, Stieltjes B, Blatow M, Mariani L, Bink A. Golden-angle radial sparse parallel (GRASP) MRI in clinical routine detection of pituitary microadenomas: First experience and feasibility. Magn Reson Imaging. 2019 Jul;60:38-43. doi: 10.1016/j.mri.2019.03.015. Epub 2019 Mar 27. PubMed PMID: 30928387.

94: Stienen MN, Bartek J Jr, Czabanka MA, Freyschlag CF, Kolias A, Krieg SM, Moojen W, Renovanz M, Sampron N, Adib SD, Schubert GA, Demetriades AK, Ringel F, Regli L, Schaller K, Meling TR; EANS Young Neurosurgeons and EANS Training Committee. Neurosurgical procedures performed during residency in Europe-preliminary numbers and time trends. Acta Neurochir (Wien). 2019 May;161(5):843-853. doi: 10.1007/s00701-019-03888-3. Epub 2019 Mar 29. PubMed PMID: 30927157.

95: Körber V, Yang J, Barah P, Wu Y, Stichel D, Gu Z, Fletcher MNC, Jones D, Hentschel B, Lamszus K, Tonn JC, Schackert G, Sabel M, Felsberg J, Zacher A, Kaulich K, Hübschmann D, Herold-Mende C, von Deimling A, Weller M, Radlwimmer B, Schlesner M, Reifenberger G, Höfer T, Lichter P. Evolutionary Trajectories of IDH(WT) Glioblastomas Reveal a Common Path of Early Tumorigenesis Instigated Years ahead of Initial Diagnosis. Cancer Cell. 2019 Apr 15;35(4):692-704.e12. doi: 10.1016/j.ccell.2019.02.007. Epub 2019 Mar 21. PubMed PMID: 30905762.

96: Ames CP, Smith JS, Pellisé F, Kelly MP, Gum JL, Alanay A, Acaroğlu E, Pérez-Grueso FJS, Kleinstück FS, Obeid I, Vila-Casademunt A, Burton DC, Lafage V, Schwab FJ, Shaffrey CI, Bess S, Serra-Burriel M; European Spine Study Group, International Spine Study Group. Development of Deployable Predictive Models for Minimal Clinically Important Difference Achievement Across the Commonly Used Health-related Quality of Life Instruments in Adult Spinal Deformity Surgery. Spine (Phila Pa 1976). 2019 Aug 15;44(16):1144-1153. doi: 10.1097/BRS.0000000000003031. PubMed PMID: 30896589.

97: Fedele T, Ramantani G, Sarnthein J. High frequency oscillations as markers of epileptogenic tissue - End of the party? Clin Neurophysiol. 2019 May;130(5):624-626. doi: 10.1016/j.clinph.2019.01.016. Epub 2019 Feb 12. PubMed PMID: 30870797.

98: Weller M, Le Rhun E. Immunotherapy for glioblastoma: quo vadis? Nat Rev Clin Oncol. 2019 Jul;16(7):405-406. doi: 10.1038/s41571-019-0195-3. PubMed PMID: 30867572.

99: Kadooka K, Hagenbuch N, Anagnostakou V, Valavanis A, Kulcsár Z. Safety and efficacy of balloon angioplasty in symptomatic intracranial stenosis: A systematic review and meta-analysis. J Neuroradiol. 2019 Mar 9. pii: S0150-9861(18)30379-1. doi: 10.1016/j.neurad.2019.02.007. [Epub ahead of print] PubMed PMID: 30862462.

100: Triplett JD, Buzzard KA, Lubomski M, Riminton DS, Barnett MH, Welgampola MS, Halmagyi GM, Nguyen M, Landau K, Lee AG, Plant GT, Fraser CL, Reddel SW, Hardy TA. Immune-mediated conditions affecting the brain, eye and ear (BEE syndromes). J Neurol Neurosurg Psychiatry. 2019 Aug;90(8):882-894. doi: 10.1136/jnnp-2018-319002. Epub 2019 Mar 9. Review. PubMed PMID: 30852493.

101: Jeszenszky D, Kaiser B, Meuli M, Fekete TF, Haschtmann D. Surgical growth guidance with non-fused anchoring segments in early-onset scoliosis. Eur Spine J. 2019 Jun;28(6):1301-1313. doi: 10.1007/s00586-019-05934-1. Epub 2019 Mar 8. Erratum in: Eur Spine J. 2019 Aug 28;:. PubMed PMID: 30848364.

102: Alisauskaite N, Cizinauskas S, Jeserevics J, Rakauskas M, Cherubini GB, Anttila M, Steffen F. Short- and long-term outcome and magnetic resonance imaging findings after surgical treatment of thoracolumbar spinal arachnoid diverticula in 25 Pugs. J Vet Intern Med. 2019 May;33(3):1376-1383. doi: 10.1111/jvim.15470. Epub 2019 Mar 7. PubMed PMID: 30844093; PubMed Central PMCID: PMC6524397.

103: Cruzeiro GAV, Salomão KB, de Biagi CAO Jr, Baumgartner M, Sturm D, Lira RCP, de Almeida Magalhães T, Baroni Milan M, da Silva Silveira V, Saggioro FP, de Oliveira RS, Dos Santos Klinger PH, Seidinger AL, Yunes JA, de Paula Queiroz RG, Oba-Shinjo SM, Scrideli CA, Nagahashi SMK, Tone LG, Valera ET. A simplified approach using Taqman low-density array for medulloblastoma subgrouping. Acta Neuropathol Commun. 2019 Mar 4;7(1):33. doi: 10.1186/s40478-019-0681-y. PubMed PMID: 30832734; PubMed Central PMCID: PMC6398239.

104: Stienen MN, Ho AL, Staartjes VE, Maldaner N, Veeravagu A, Desai A, Gautschi OP, Bellut D, Regli L, Ratliff JK, Park J. Objective measures of functional impairment for degenerative diseases of the lumbar spine: a systematic review of the literature. Spine J. 2019 Jul;19(7):1276-1293. doi: 10.1016/j.spinee.2019.02.014. Epub 2019 Mar 2. Review. PubMed PMID: 30831316.

105: Velz J, Neidert MC, Lauk O, Inci I, Bellut D, Rushing E. A 32-Year-Old Women with an Intra- and Paraspinal, Extradural Mass at T10-T12. Brain Pathol. 2019 Mar;29(2):309-310. doi: 10.1111/bpa.12708. PubMed PMID: 30821031.

106: Sze L, Tschopp O, Neidert MC, Bernays RL, Ghirlanda C, Zwimpfer C, Wiesli P, Schmid C. Soluble delta-like 1 homolog decreases in patients with acromegaly following pituitary surgery: A potential mediator of adipogenesis suppression by growth hormone? Growth Horm IGF Res. 2019 Apr;45:20-24. doi: 10.1016/j.ghir.2019.02.002. Epub 2019 Feb 18. Erratum in: Growth Horm IGF Res. 2019 Aug 26;:. PubMed PMID: 30818110.

107: Klement RJ, Abbasi-Senger N, Adebahr S, Alheid H, Allgaeuer M, Becker G, Blanck O, Boda-Heggemann J, Brunner T, Duma M, Eble MJ, Ernst I, Gerum S, Habermehl D, Hass P, Henkenberens C, Hildebrandt G, Imhoff D, Kahl H, Klass ND, Krempien R, Lewitzki V, Lohaus F, Ostheimer C, Papachristofilou A, Petersen C, Rieber J, Schneider T, Schrade E, Semrau R, Wachter S, Wittig A, Guckenberger M, Andratschke N. The impact of local control on overall survival after stereotactic body radiotherapy for liver and lung metastases from colorectal cancer: a combined analysis of 388 patients with 500 metastases. BMC Cancer. 2019 Feb 26;19(1):173. doi: 10.1186/s12885-019-5362-5. PubMed PMID: 30808323; PubMed Central PMCID: PMC6390357.

108: Serra C, Regli L. Response to: “No doubt: the invasion of the cavernous sinus is the limiting factor for complete resection in pituitary neuroendocrine tumors”. Acta Neurochir (Wien). 2019 Apr;161(4):719-720. doi: 10.1007/s00701-018-03787-z. Epub 2019 Feb 26. PubMed PMID: 30806778.

109: Zarb Y, Weber-Stadlbauer U, Kirschenbaum D, Kindler DR, Richetto J, Keller D, Rademakers R, Dickson DW, Pasch A, Byzova T, Nahar K, Voigt FF, Helmchen F, Boss A, Aguzzi A, Klohs J, Keller A. Ossified blood vessels in primary familial brain calcification elicit a neurotoxic astrocyte response. Brain. 2019 Apr 1;142(4):885-902. doi: 10.1093/brain/awz032. PubMed PMID: 30805583; PubMed Central PMCID: PMC6439320.

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112: Herrlinger U, Tzaridis T, Mack F, Steinbach JP, Schlegel U, Sabel M, Hau P, Kortmann RD, Krex D, Grauer O, Goldbrunner R, Schnell O, Bähr O, Uhl M, Seidel C, Tabatabai G, Kowalski T, Ringel F, Schmidt-Graf F, Suchorska B, Brehmer S, Weyerbrock A, Renovanz M, Bullinger L, Galldiks N, Vajkoczy P, Misch M, Vatter H, Stuplich M, Schäfer N, Kebir S, Weller J, Schaub C, Stummer W, Tonn JC, Simon M, Keil VC, Nelles M, Urbach H, Coenen M, Wick W, Weller M, Fimmers R, Schmid M, Hattingen E, Pietsch T, Coch C, Glas M; Neurooncology Working Group of the German Cancer Society. Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA-09): a randomised, open-label, phase 3 trial. Lancet. 2019 Feb 16;393(10172):678-688. doi: 10.1016/S0140-6736(18)31791-4. Epub 2019 Feb 14. PubMed PMID: 30782343.

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114: Nieder C, Guckenberger M, Gaspar LE, Rusthoven CG, De Ruysscher D, Sahgal A, Nguyen T, Grosu AL, Mehta MP. Management of patients with brain metastases from non-small cell lung cancer and adverse prognostic features: multi-national radiation treatment recommendations are heterogeneous. Radiat Oncol. 2019 Feb 15;14(1):33. doi: 10.1186/s13014-019-1237-9. PubMed PMID: 30770745; PubMed Central PMCID: PMC6377775.

115: Pires da Silva I, Glitza IC, Haydu LE, Johnpulle R, Banks PD, Grass GD, Goldinger SMA, Smith JL, Everett AS, Koelblinger P, Roberts-Thomson R, Millward M, Atkinson VG, Guminski A, Kapoor R, Conry RM, Carlino MS, Wang W, Shackleton MJ, Eroglu Z, Lo S, Hong AM, Long GV, Johnson DB, Menzies AM. Incidence, features and management of radionecrosis in melanoma patients treated with cerebral radiotherapy and anti-PD-1 antibodies. Pigment Cell Melanoma Res. 2019 Jul;32(4):553-563. doi: 10.1111/pcmr.12775. Epub 2019 Mar 3. PubMed PMID: 30767428.

116: Hendrik Bas van Niftrik C, Sebök M, Muscas G, Piccirelli M, Serra C, Krayenbühl N, Pangalu A, Bozinov O, Luft A, Stippich C, Regli L, Fierstra J. Characterizing ipsilateral thalamic diaschisis in symptomatic cerebrovascular steno-occlusive patients. J Cereb Blood Flow Metab. 2019 Feb 12:271678×19830532. doi: 10.1177/0271678×19830532. [Epub ahead of print] PubMed PMID: 30755133.

117: Hauser TK, Seeger A, Bender B, Klose U, Thurow J, Ernemann U, Tatagiba M, Meyer PT, Khan N, Roder C. Hypercapnic BOLD MRI compared to H(2)(15)O PET/CT for the hemodynamic evaluation of patients with Moyamoya Disease. Neuroimage Clin. 2019;22:101713. doi: 10.1016/j.nicl.2019.101713. Epub 2019 Feb 4. PubMed PMID: 30743136; PubMed Central PMCID: PMC6370561.

118: Stienen MN, Smoll NR, Fung C, Goldberg J, Bervini D, Maduri R, Chiappini A, Robert T, May A, Bijlenga P, Zumofen D, Roethlisberger M, Seule MA, Marbacher S, Fandino J, Schatlo B, Schaller K, Keller E, Bozinov O, Regli L; Swiss SOS Study Group. Home-Time as a Surrogate Marker for Functional Outcome After Aneurysmal Subarachnoid Hemorrhage. Stroke. 2018 Dec;49(12):3081-3084. doi: 10.1161/STROKEAHA.118.022808. PubMed PMID: 30735342.

119: Gallay MN, Moser D, Federau C, Jeanmonod D. Anatomical and Technical Reappraisal of the Pallidothalamic Tractotomy With the Incisionless Transcranial MR-Guided Focused Ultrasound. A Technical Note. Front Surg. 2019 Jan 24;6:2. doi: 10.3389/fsurg.2019.00002. eCollection 2019. PubMed PMID: 30733946; PubMed Central PMCID: PMC6353787.

120: Müller MD, Jongen LM, Altinbas A, Blackham KA, Nederkoorn PJ, Macdonald S, Jäger R, Wolff T, Lyrer PA, Kappelle LJ, Wetzel SG, Richards T, Hendrikse J, de Borst GJ, van der Worp HB, Engelter ST, Werring DJ, Brown MM, Bonati LH; ICSS-MRI Study Investigators. Silent Intracerebral Hemorrhage in Patients Randomized to Stenting or Endarterectomy for Symptomatic Carotid Stenosis. J Stroke. 2019 Jan;21(1):116-119. doi: 10.5853/jos.2018.02838. Epub 2019 Jan 31. PubMed PMID: 30732448; PubMed Central PMCID: PMC6372891.

121: Post R, Germans MR, Boogaarts HD, Ferreira Dias Xavier B, Van den Berg R, Coert BA, Vandertop WP, Verbaan D. Short-term tranexamic acid treatment reduces in-hospital mortality in aneurysmal sub-arachnoid hemorrhage: A multicenter comparison study. PLoS One. 2019 Feb 7;14(2):e0211868. doi: 10.1371/journal.pone.0211868. eCollection 2019. PubMed PMID: 30730957; PubMed Central PMCID: PMC6366882.

122: Yang Y, van Niftrik B, Ma X, Velz J, Wang S, Regli L, Bozinov O. Analysis of safe entry zones into the brainstem. Neurosurg Rev. 2019 Sep;42(3):721-729. doi: 10.1007/s10143-019-01081-9. Epub 2019 Feb 6. PubMed PMID: 30726522.

123: Akeret K, Germans M, Sun W, Kulcsar Z, Regli L. Subarachnoid hemorrhage due to flow-related dissection of the posterior inferior cerebellar artery associated with a distal arteriovenous malformation. World Neurosurg. 2019 Feb 2. pii: S1878-8750(19)30248-7. doi: 10.1016/j.wneu.2019.01.148. [Epub ahead of print] PubMed PMID: 30721771.

124: Muscas G, Bas van Niftrik CH, Fierstra J, Piccirelli M, Sebök M, Burkhardt JK, Valavanis A, Pangalu A, Regli L, Bozinov O. Feasibility and safety of intraoperative BOLD functional MRI cerebrovascular reactivity to evaluate extracranial-to-intracranial bypass efficacy. Neurosurg Focus. 2019 Feb 1;46(2):E7. doi: 10.3171/2018.11.FOCUS18502. PubMed PMID: 30717072.

125: Le Rhun E, Devos P, Boulanger T, Smits M, Brandsma D, Rudà R, Furtner J, Hempel JM, Postma TJ, Roth P, Snijders TJ, Winkler F, Winklhofer S, Castellano A, Hattingen E, Capellades J, Gorlia T, Van den Bent M, Wen PY, Bendszus M, Weller M; European Organisation for Research and Treatment of Cancer (EORTC) Brain Tumor Group (BTG) Central Nervous System (CNS) Metastases Committee and the EORTC BTG Imaging Committee. The RANO Leptomeningeal Metastasis Group proposal to assess response to treatment: lack of feasibility and clinical utility and a revised proposal. Neuro Oncol. 2019 May 6;21(5):648-658. doi: 10.1093/neuonc/noz024. PubMed PMID: 30715514; PubMed Central PMCID: PMC6502503.

126: Akeret K, Serra C, Rafi O, Staartjes VE, Fierstra J, Bellut D, Maldaner N, Imbach LL, Wolpert F, Poryazova R, Regli L, Krayenbühl N. Anatomical features of primary brain tumors affect seizure risk and semiology. Neuroimage Clin. 2019;22:101688. doi: 10.1016/j.nicl.2019.101688. Epub 2019 Jan 25. PubMed PMID: 30710869; PubMed Central PMCID: PMC6354289.

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128: Vasella F, Velz J, Neidert MC, Henzi S, Sarnthein J, Krayenbühl N, Bozinov O, Regli L, Stienen MN. Safety of resident training in the microsurgical resection of intracranial tumors: Data from a prospective registry of complications and outcome. Sci Rep. 2019 Jan 30;9(1):954. doi: 10.1038/s41598-018-37533-3. PubMed PMID: 30700746; PubMed Central PMCID: PMC6353994.

129: Staartjes VE, Beusekamp F, Schröder ML. Can objective functional impairment in lumbar degenerative disease be reliably assessed at home using the five-repetition sit-to-stand test? A prospective study. Eur Spine J. 2019 Apr;28(4):665-673. doi: 10.1007/s00586-019-05897-3. Epub 2019 Jan 24. PubMed PMID: 30680635.

130: Maduri R, Starnoni D, Rocca A, Bervini D, Zumofen DW, Stienen MN, Schatlo B, Fung C, Robert T, Seule MA, Burkhardt JK, Maldaner N, Rothlisberger M, Blackham KA, Marbacher S, D'Alonzo D, Remonda L, Machi P, Gralla J, Bijlenga P, Saliou G, Ballabeni P, Levivier M, Messerer M, Daniel RT; Swiss SOS Group. Ruptured posterior circulation aneurysms: epidemiology, patterns of care, and outcomes from the Swiss SOS national registry. Acta Neurochir (Wien). 2019 Apr;161(4):769-779. doi: 10.1007/s00701-019-03812-9. Epub 2019 Jan 25. Erratum in: Acta Neurochir (Wien). 2019 Feb 23;:. PubMed PMID: 30680461.

131: Boire A, Brandsma D, Brastianos PK, Le Rhun E, Ahluwalia M, Junck L, Glantz M, Groves MD, Lee EQ, Lin N, Raizer J, Rudà R, Weller M, Van den Bent MJ, Vogelbaum MA, Chang S, Wen PY, Soffietti R. Liquid biopsy in central nervous system metastases: a RANO review and proposals for clinical applications. Neuro Oncol. 2019 May 6;21(5):571-584. doi: 10.1093/neuonc/noz012. PubMed PMID: 30668804; PubMed Central PMCID: PMC6502489.

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133: Krauss P, Oertel MF, Stieglitz LH. Introduction of a self-holding retractor for optimized abdominal visualization in ventriculoperitoneal shunt surgery: first experiences at a single center. Acta Neurochir (Wien). 2019 Jul;161(7):1361-1365. doi: 10.1007/s00701-018-03794-0. Epub 2019 Jan 11. PubMed PMID: 30635726.

134: Ames CP, Smith JS, Pellisé F, Kelly M, Alanay A, Acaroğlu E, Pérez-Grueso FJS, Kleinstück F, Obeid I, Vila-Casademunt A, Shaffrey CI Jr, Burton D, Lafage V, Schwab F, Shaffrey CI Sr, Bess S, Serra-Burriel M; European Spine Study Group, International Spine Study Group. Artificial Intelligence Based Hierarchical Clustering of Patient Types and Intervention Categories in Adult Spinal Deformity Surgery: Towards a New Classification Scheme that Predicts Quality and Value. Spine (Phila Pa 1976). 2019 Jan 7. doi: 10.1097/BRS.0000000000002974. [Epub ahead of print] PubMed PMID: 30633115.

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136: Yeates KO, Tang K, Barrowman N, Freedman SB, Gravel J, Gagnon I, Sangha G, Boutis K, Beer D, Craig W, Burns E, Farion KJ, Mikrogianakis A, Barlow K, Dubrovsky AS, Meeuwisse W, Gioia G, Meehan WP 3rd, Beauchamp MH, Kamil Y, Grool AM, Hoshizaki B, Anderson P, Brooks BL, Vassilyadi M, Klassen T, Keightley M, Richer L, DeMatteo C, Osmond MH, Zemek R; Pediatric Emergency Research Canada (PERC) Predicting Persistent Postconcussive Problems in Pediatrics (5P) Concussion Team. Derivation and Initial Validation of Clinical Phenotypes of Children Presenting with Concussion Acutely in the Emergency Department: Latent Class Analysis of a Multi-Center, Prospective Cohort, Observational Study. J Neurotrauma. 2019 Jun;36(11):1758-1767. doi: 10.1089/neu.2018.6009. Epub 2019 Mar 6. PubMed PMID: 30618356.

137: Jilg A, Bechstein P, Saade A, Dick M, Li TX, Tosini G, Rami A, Zemmar A, Stehle JH. Melatonin modulates daytime-dependent synaptic plasticity and learning efficiency. J Pineal Res. 2019 Apr;66(3):e12553. doi: 10.1111/jpi.12553. Epub 2019 Feb 14. PubMed PMID: 30618149; PubMed Central PMCID: PMC6405292.

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143: Seoane J, De Mattos-Arruda L, Le Rhun E, Bardelli A, Weller M. Cerebrospinal fluid cell-free tumour DNA as a liquid biopsy for primary brain tumours and central nervous system metastases. Ann Oncol. 2019 Feb 1;30(2):211-218. doi: 10.1093/annonc/mdy544. PubMed PMID: 30576421.

144: Akeret K, Vasella F, Geisseler O, Dannecker N, Ghosh A, Brugger P, Regli L, Stienen MN. Time to be “smart”-Opportunities Arising From Smartphone-Based Behavioral Analysis in Daily Patient Care. Front Behav Neurosci. 2018 Dec 4;12:303. doi: 10.3389/fnbeh.2018.00303. eCollection 2018. PubMed PMID: 30568582; PubMed Central PMCID: PMC6290758.

145: Salatzki J, Liechti MD, Spanudakis E, Gonzales G, Baldwin J, Haslam C, Pakzad M, Panicker JN. Factors influencing return for maintenance treatment with percutaneous tibial nerve stimulation for the management of the overactive bladder. BJU Int. 2019 May;123(5A):E20-E28. doi: 10.1111/bju.14651. Epub 2019 Feb 3. PubMed PMID: 30552801.

146: Bilich T, Nelde A, Bichmann L, Roerden M, Salih HR, Kowalewski DJ, Schuster H, Tsou CC, Marcu A, Neidert MC, Lübke M, Rieth J, Schemionek M, Brümmendorf TH, Vucinic V, Niederwieser D, Bauer J, Märklin M, Peper JK, Klein R, Kohlbacher O, Kanz L, Rammensee HG, Stevanović S, Walz JS. The HLA ligandome landscape of chronic myeloid leukemia delineates novel T-cell epitopes for immunotherapy. Blood. 2019 Feb 7;133(6):550-565. doi: 10.1182/blood-2018-07-866830. Epub 2018 Dec 10. PubMed PMID: 30530751.

147: Abbas M, de Kraker MEA, Aghayev E, Astagneau P, Aupee M, Behnke M, Bull A, Choi HJ, de Greeff SC, Elgohari S, Gastmeier P, Harrison W, Koek MBG, Lamagni T, Limon E, Løwer HL, Lyytikäinen O, Marimuthu K, Marquess J, McCann R, Prantner I, Presterl E, Pujol M, Reilly J, Roberts C, Segagni Lusignani L, Si D, Szilágyi E, Tanguy J, Tempone S, Troillet N, Worth LJ, Pittet D, Harbarth S. Impact of participation in a surgical site infection surveillance network: results from a large international cohort study. J Hosp Infect. 2019 Jul;102(3):267-276. doi: 10.1016/j.jhin.2018.12.003. Epub 2018 Dec 7. PubMed PMID: 30529703.

148: Law I, Albert NL, Arbizu J, Boellaard R, Drzezga A, Galldiks N, la Fougère C, Langen KJ, Lopci E, Lowe V, McConathy J, Quick HH, Sattler B, Schuster DM, Tonn JC, Weller M. Joint EANM/EANO/RANO practice guidelines/SNMMI procedure standards for imaging of gliomas using PET with radiolabelled amino acids and [(18)F]FDG: version 1.0. Eur J Nucl Med Mol Imaging. 2019 Mar;46(3):540-557. doi: 10.1007/s00259-018-4207-9. Epub 2018 Dec 5. PubMed PMID: 30519867; PubMed Central PMCID: PMC6351513.

149: Kogias E, Schmeiser B, Doostkam S, Brandt A, Hammen T, Zentner J, Ramantani G. Multilobar Resections for 3T MRI-Negative Epilepsy: Worth the Trouble? World Neurosurg. 2019 Mar;123:e338-e347. doi: 10.1016/j.wneu.2018.11.170. Epub 2018 Nov 28. PubMed PMID: 30502474.

150: Hegi ME, Genbrugge E, Gorlia T, Stupp R, Gilbert MR, Chinot OL, Nabors LB, Jones G, Van Criekinge W, Straub J, Weller M. MGMT Promoter Methylation Cutoff with Safety Margin for Selecting Glioblastoma Patients into Trials Omitting Temozolomide: A Pooled Analysis of Four Clinical Trials. Clin Cancer Res. 2019 Mar 15;25(6):1809-1816. doi: 10.1158/1078-0432.CCR-18-3181. Epub 2018 Dec 4. PubMed PMID: 30514777.

151: Hagemann J, Roesner J, Helling S, Jacobi C, Doescher J, Engelbarts M, Kuenzel J, Krauss P, Becker S, Betz CS. Long-term Outcome for Open and Endoscopically Resected Sinonasal Tumors. Otolaryngol Head Neck Surg. 2019 May;160(5):862-869. doi: 10.1177/0194599818815881. Epub 2018 Dec 4. PubMed PMID: 30511889.

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153: Schütz A, Murek M, Stieglitz LH, Bernasconi C, Vulcu S, Beck J, Raabe A, Schucht P. ACE-inhibitors: a preventive measure for bone flap resorption after autologous cranioplasty? J Neurosurg. 2018 Nov 1:1-8. doi: 10.3171/2018.6.JNS172605. [Epub ahead of print] PubMed PMID: 30497161.

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2: From the American Association of Neurological Surgeons (AANS), American Society of Neuroradiology (ASNR), Cardiovascular and Interventional Radiology Society of Europe (CIRSE), Canadian Interventional Radiology Association (CIRA), Congress of Neurological Surgeons (CNS), European Society of Minimally Invasive Neurological Therapy (ESMINT), European Society of Neuroradiology (ESNR), European Stroke Organization (ESO), Society for Cardiovascular Angiography and Interventions (SCAI), Society of Interventional Radiology (SIR), Society of NeuroInterventional Surgery (SNIS), and World Stroke Organization (WSO), Sacks D, Baxter B, Campbell BCV, Carpenter JS, Cognard C, Dippel D, Eesa M, Fischer U, Hausegger K, Hirsch JA, Shazam Hussain M, Jansen O, Jayaraman MV, Khalessi AA, Kluck BW, Lavine S, Meyers PM, Ramee S, Rüfenacht DA, Schirmer CM, Vorwerk D. Multisociety Consensus Quality Improvement Revised Consensus Statement for Endovascular Therapy of Acute Ischemic Stroke. Int J Stroke. 2018 Aug;13(6):612-632. doi: 10.1177/1747493018778713. Epub 2018 May 22. PubMed PMID: 29786478.

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36: Meuwly C, Chowdhury T, Sandu N, Golanov E, Erne P, Rosemann T, Schaller B. Definition and Diagnosis of the Trigeminocardiac Reflex: A Grounded Theory Approach for an Update. Front Neurol. 2017 Oct 9;8:533. doi: 10.3389/fneur.2017.00533. eCollection 2017. Review. PubMed PMID: 29085328; PubMed Central PMCID: PMC5649131.

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42: Maillard LG, Tassi L, Bartolomei F, Catenoix H, Dubeau F, Szurhaj W, Kahane P, Nica A, Marusic P, Mindruta I, Chassoux F, Ramantani G. Stereoelectroencephalography and surgical outcome in polymicrogyria-related epilepsy: A multicentric study. Ann Neurol. 2017 Nov;82(5):781-794. doi: 10.1002/ana.25081. Epub 2017 Nov 11. PubMed PMID: 29059488.

43: Renfrow JJ, Weller M, Strowd RE. Meeting Update-World Federation of Neuro-Oncology Societies (WFNOS) Meeting 2017. Neuro Oncol. 2017 Oct 19;19(11):1457-1459. doi: 10.1093/neuonc/nox184. PubMed PMID: 29059448; PubMed Central PMCID: PMC5737526.

44: Habraken SJM, Sharfo AWM, Buijsen J, Verbakel WFAR, Haasbeek CJA, Öllers MC, Westerveld H, van Wieringen N, Reerink O, Seravalli E, Braam PM, Wendling M, Lacornerie T, Mirabel X, Weytjens R, Depuydt L, Tanadini-Lang S, Riesterer O, Haustermans K, Depuydt T, Dwarkasing RS, Willemssen FEJA, Heijmen BJM, Méndez Romero A. The TRENDY multi-center randomized trial on hepatocellular carcinoma - Trial QA including automated treatment planning and benchmark-case results. Radiother Oncol. 2017 Dec;125(3):507-513. doi: 10.1016/j.radonc.2017.09.007. Epub 2017 Oct 16. PubMed PMID: 29050954.

45: Krauss P, Fritz-Naville M, Regli L, Stieglitz LH. Progressive Functional Underdrainage in Cerebrospinal Fluid Shunt-Dependent Women During Pregnancy: Case Report and Review of the Literature. World Neurosurg. 2018 Jan;109:372-376. doi: 10.1016/j.wneu.2017.09.108. Epub 2017 Oct 14. Review. PubMed PMID: 29038081.

46: Burkhardt JK, Winklhofer S, Fierstra J, Wegener S, Esposito G, Luft A, Bozinov O, Regli L. Emergency Extracranial-Intracranial Bypass to Revascularize Salvageable Brain Tissue in Acute Ischemic Stroke Patients. World Neurosurg. 2018 Jan;109:e476-e485. doi: 10.1016/j.wneu.2017.10.005. Epub 2017 Oct 12. PubMed PMID: 29032219.

47: Beyer U, Brand F, Martens H, Weder J, Christians A, Elyan N, Hentschel B, Westphal M, Schackert G, Pietsch T, Hong B, Krauss JK, Samii A, Raab P, Das A, Dumitru CA, Sandalcioglu IE, Hakenberg OW, Erbersdobler A, Lehmann U, Reifenberger G, Weller M, Reijns MAM, Preller M, Wiese B, Hartmann C, Weber RG. Rare ADAR and RNASEH2B variants and a type I interferon signature in glioma and prostate carcinoma risk and tumorigenesis. Acta Neuropathol. 2017 Dec;134(6):905-922. doi: 10.1007/s00401-017-1774-y. Epub 2017 Oct 13. PubMed PMID: 29030706.

48: Moransard M, Bednar M, Frei K, Gassmann M, Ogunshola OO. Erythropoietin reduces experimental autoimmune encephalomyelitis severity via neuroprotective mechanisms. J Neuroinflammation. 2017 Oct 13;14(1):202. doi: 10.1186/s12974-017-0976-5. PubMed PMID: 29029628; PubMed Central PMCID: PMC5640948.

49: Mindermann T, Mack A. Proton-beam therapy or photon-beam radiosurgery for WHO grade I meningiomas? Acta Neurochir (Wien). 2017 Dec;159(12):2401-2403. doi: 10.1007/s00701-017-3353-3. Epub 2017 Oct 13. PubMed PMID: 29027014.

50: Neidert MC, Lawton MT, Kim LJ, Nerva JD, Kurisu K, Ikawa F, Konczalla J, Dinc N, Seifert V, Habdank-Kolaczkowski J, Hatano T, Hayase M, Podlesek D, Schackert G, Wanet T, Gläsker S, Griessenauer CJ, Ogilvy CS, Kneist A, Sure U, Seifert B, Regli L, Bozinov O, Burkhardt JK. International multicentre validation of the arteriovenous malformation-related intracerebral haemorrhage (AVICH) score. J Neurol Neurosurg Psychiatry. 2017 Oct 6. pii: jnnp-2017-316259. doi: 10.1136/jnnp-2017-316259. [Epub ahead of print] PubMed PMID: 28986471.

51: Fierstra J, van Niftrik C, Piccirelli M, Bozinov O, Pangalu A, Krayenbühl N, Valavanis A, Weller M, Regli L. Diffuse gliomas exhibit whole brain impaired cerebrovascular reactivity. Magn Reson Imaging. 2018 Jan;45:78-83. doi: 10.1016/j.mri.2017.09.017. Epub 2017 Oct 3. PubMed PMID: 28986176.

52: Yilgor C, Sogunmez N, Boissiere L, Yavuz Y, Obeid I, Kleinstück F, Pérez-Grueso FJS, Acaroglu E, Haddad S, Mannion AF, Pellise F, Alanay A; European Spine Study Group (ESSG). Global Alignment and Proportion (GAP) Score: Development and Validation of a New Method of Analyzing Spinopelvic Alignment to Predict Mechanical Complications After Adult Spinal Deformity Surgery. J Bone Joint Surg Am. 2017 Oct 4;99(19):1661-1672. doi: 10.2106/JBJS.16.01594. PubMed PMID: 28976431.

53: Voormolen EHJ, Diederen S, van Stralen M, Woerdeman PA, Noordmans HJ, Viergever MA, Regli L, Robe PA, Berkelbach van der Sprenkel JW. Benchmarking Distance Control and Virtual Drilling for Lateral Skull Base Surgery. World Neurosurg. 2018 Jan;109:e217-e228. doi: 10.1016/j.wneu.2017.09.142. Epub 2017 Sep 29. PubMed PMID: 28966150.

54: Mackay A, Burford A, Carvalho D, Izquierdo E, Fazal-Salom J, Taylor KR, Bjerke L, Clarke M, Vinci M, Nandhabalan M, Temelso S, Popov S, Molinari V, Raman P, Waanders AJ, Han HJ, Gupta S, Marshall L, Zacharoulis S, Vaidya S, Mandeville HC, Bridges LR, Martin AJ, Al-Sarraj S, Chandler C, Ng HK, Li X, Mu K, Trabelsi S, Brahim DH, Kisljakov AN, Konovalov DM, Moore AS, Carcaboso AM, Sunol M, de Torres C, Cruz O, Mora J, Shats LI, Stavale JN, Bidinotto LT, Reis RM, Entz-Werle N, Farrell M, Cryan J, Crimmins D, Caird J, Pears J, Monje M, Debily MA, Castel D, Grill J, Hawkins C, Nikbakht H, Jabado N, Baker SJ, Pfister SM, Jones DTW, Fouladi M, von Bueren AO, Baudis M, Resnick A, Jones C. Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma. Cancer Cell. 2017 Oct 9;32(4):520-537.e5. doi: 10.1016/j.ccell.2017.08.017. Epub 2017 Sep 28. PubMed PMID: 28966033; PubMed Central PMCID: PMC5637314.

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58: Kadri PAS, de Oliveira JG, Krayenbühl N, Türe U, de Oliveira EPL, Al-Mefty O, Ribas GC. Surgical Approaches to the Temporal Horn: An Anatomic Analysis of White Matter Tract Interruption. Oper Neurosurg (Hagerstown). 2017 Apr 1;13(2):258-270. doi: 10.1093/ons/opw011. PubMed PMID: 28927207.

59: Bellut D, Burkhardt JK, Schultze D, Ginsberg HJ, Regli L, Sarnthein J. Validating a therapy-oriented complication grading system in lumbar spine surgery: a prospective population-based study. Sci Rep. 2017 Sep 18;7(1):11752. doi: 10.1038/s41598-017-12038-7. PubMed PMID: 28924249; PubMed Central PMCID: PMC5603580.

60: Guentchev M, Preuss C, Rink R, Peter L, Sailer MHM, Tuettenberg J. Long-Term Reduction of Sacroiliac Joint Pain With Peripheral Nerve Stimulation. Oper Neurosurg (Hagerstown). 2017 Oct 1;13(5):634-639. doi: 10.1093/ons/opx017. PubMed PMID: 28922873.

61: Korkmaz E, Kleinloog R, Verweij BH, Allijn IE, Hekking LHP, Regli L, Rinkel GJE, Ruigrok YM, Andries Post J. Comparative Ultrastructural and Stereological Analyses of Unruptured and Ruptured Saccular Intracranial Aneurysms. J Neuropathol Exp Neurol. 2017 Oct 1;76(10):908-916. doi: 10.1093/jnen/nlx075. PubMed PMID: 28922850.

62: Moustakis C, Blanck O, Ebrahimi F, Ka Heng Chan M, Ernst I, Krieger T, Duma MN, Oechsner M, Ganswindt U, Heinz C, Alheit H, Blank H, Nestle U, Wiehle R, Kornhuber C, Ostheimer C, Petersen C, Pollul G, Baus W, Altenstein G, Beckers E, Jurianz K, Sterzing F, Kretschmer M, Seegenschmiedt H, Maass T, Droege S, Wolf U, Schoeffler J, Haverkamp U, Eich H, Guckenberger M. Time for standardization of SBRT planning through large scale clinical data and guideline-based approaches. Strahlenther Onkol. 2017 Dec;193(12):1068-1069. doi: 10.1007/s00066-017-1216-8. Epub 2017 Sep 15. PubMed PMID: 28916902.

63: Schreglmann SR, Riederer F, Galovic M, Ganos C, Kägi G, Waldvogel D, Jaunmuktane Z, Schaller A, Hidding U, Krasemann E, Michels L, Baumann CR, Bhatia K, Jung HH. Movement disorders in genetically confirmed mitochondrial disease and the putative role of the cerebellum. Mov Disord. 2018 Jan;33(1):146-155. doi: 10.1002/mds.27174. Epub 2017 Sep 13. PubMed PMID: 28901595.

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66: Bensler S, Sutter R, Pfirrmann CWA, Peterson CK. Particulate versus non-particulate corticosteroids for transforaminal nerve root blocks: Comparison of outcomes in 494 patients with lumbar radiculopathy. Eur Radiol. 2018 Mar;28(3):946-952. doi: 10.1007/s00330-017-5045-z. Epub 2017 Sep 11. PubMed PMID: 28894933.

67: Roesch J, Cho JBC, Fahim DK, Gerszten PC, Flickinger JC, Grills IS, Jawad M, Kersh R, Letourneau D, Mantel F, Sahgal A, Shin JH, Winey B, Guckenberger M. Risk for surgical complications after previous stereotactic body radiotherapy of the spine. Radiat Oncol. 2017 Sep 11;12(1):153. doi: 10.1186/s13014-017-0887-8. PubMed PMID: 28893299; PubMed Central PMCID: PMC5594477.

68: Joswig H, Korte W, Früh S, Epprecht L, Hildebrandt G, Fournier JY, Stienen MN. Neurodegenerative cerebrospinal fluid biomarkers tau and amyloid beta predict functional, quality of life, and neuropsychological outcomes after aneurysmal subarachnoid hemorrhage. Neurosurg Rev. 2018 Apr;41(2):605-614. doi: 10.1007/s10143-017-0900-6. Epub 2017 Sep 10. PubMed PMID: 28890998.

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84: De La Fuente AG, Lange S, Silva ME, Gonzalez GA, Tempfer H, van Wijngaarden P, Zhao C, Di Canio L, Trost A, Bieler L, Zaunmair P, Rotheneichner P, O'Sullivan A, Couillard-Despres S, Errea O, Mäe MA, Andrae J, He L, Keller A, Bátiz LF, Betsholtz C, Aigner L, Franklin RJM, Rivera FJ. Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination. Cell Rep. 2017 Aug 22;20(8):1755-1764. doi: 10.1016/j.celrep.2017.08.007. PubMed PMID: 28834740; PubMed Central PMCID: PMC5574064.

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91: Kirschenbaum D, Prömmel P, Vasella F, Haralambieva E, Marques Maggio E, Reisch R, Beer M, Camenisch U, Rushing EJ. Fibrin-associated diffuse large B-cell lymphoma in a hemorrhagic cranial arachnoid cyst. Acta Neuropathol Commun. 2017 Aug 7;5(1):60. doi: 10.1186/s40478-017-0463-3. PubMed PMID: 28784166; PubMed Central PMCID: PMC5545859.

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113: Ehrbar S, Jöhl A, Tartas A, Stark LS, Riesterer O, Klöck S, Guckenberger M, Tanadini-Lang S. ITV, mid-ventilation, gating or couch tracking - A comparison of respiratory motion-management techniques based on 4D dose calculations. Radiother Oncol. 2017 Jul;124(1):80-88. doi: 10.1016/j.radonc.2017.05.016. Epub 2017 Jun 3. PubMed PMID: 28587761.

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164: Giuliani M, Hope A, Guckenberger M, Mantel F, Peulen H, Sonke JJ, Belderbos J, Werner-Wasik M, Ye H, Grills IS. Stereotactic Body Radiation Therapy in Octo- and Nonagenarians for the Treatment of Early-Stage Lung Cancer. Int J Radiat Oncol Biol Phys. 2017 Jul 15;98(4):893-899. doi: 10.1016/j.ijrobp.2017.01.019. Epub 2017 Jan 9. PubMed PMID: 28258901.

165: Traenka C, Dougoud D, Simonetti BG, Metso TM, Debette S, Pezzini A, Kloss M, Grond-Ginsbach C, Majersik JJ, Worrall BB, Leys D, Baumgartner R, Caso V, Béjot Y, Compter A, Reiner P, Thijs V, Southerland AM, Bersano A, Brandt T, Gensicke H, Touzé E, Martin JJ, Chabriat H, Tatlisumak T, Lyrer P, Arnold M, Engelter ST; CADISP-Plus Study Group. Cervical artery dissection in patients ≥60 years: Often painless, few mechanical triggers. Neurology. 2017 Apr 4;88(14):1313-1320. doi: 10.1212/WNL.0000000000003788. Epub 2017 Mar 3. PubMed PMID: 28258079.

166: Emery CA, Black AM, Kolstad A, Martinez G, Nettel-Aguirre A, Engebretsen L, Johnston K, Kissick J, Maddocks D, Tator C, Aubry M, Dvořák J, Nagahiro S, Schneider K. What strategies can be used to effectively reduce the risk of concussion in sport? A systematic review. Br J Sports Med. 2017 Jun;51(12):978-984. doi: 10.1136/bjsports-2016-097452. Epub 2017 Mar 2. Review. PubMed PMID: 28254746.

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170: van Lieshout JH, Dibué-Adjei M, Cornelius JF, Slotty PJ, Schneider T, Restin T, Boogaarts HD, Steiger HJ, Petridis AK, Kamp MA. An introduction to the pathophysiology of aneurysmal subarachnoid hemorrhage. Neurosurg Rev. 2018 Oct;41(4):917-930. doi: 10.1007/s10143-017-0827-y. Epub 2017 Feb 18. Review. PubMed PMID: 28215029.

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193: Pomares FB, Funck T, Feier NA, Roy S, Daigle-Martel A, Ceko M, Narayanan S, Araujo D, Thiel A, Stikov N, Fitzcharles MA, Schweinhardt P. Histological Underpinnings of Grey Matter Changes in Fibromyalgia Investigated Using Multimodal Brain Imaging. J Neurosci. 2017 Feb 1;37(5):1090-1101. doi: 10.1523/JNEUROSCI.2619-16.2016. Epub 2016 Dec 16. PubMed PMID: 27986927.

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196: Guo DC, Duan XY, Regalado ES, Mellor-Crummey L, Kwartler CS, Kim D, Lieberman K, de Vries BBA, Pfundt R, Schinzel A, Kotzot D, Shen X, Yang ML; University of Washington Center for Mendelian Genomics, Bamshad MJ, Nickerson DA, Gornik HL, Ganesh SK, Braverman AC, Grange DK, Milewicz DM. Loss-of-Function Mutations in YY1AP1 Lead to Grange Syndrome and a Fibromuscular Dysplasia-Like Vascular Disease. Am J Hum Genet. 2017 Jan 5;100(1):21-30. doi: 10.1016/j.ajhg.2016.11.008. Epub 2016 Dec 8. PubMed PMID: 27939641; PubMed Central PMCID: PMC5223026.

197: Wälchli T, Ulmann-Schuler A, Hintermüller C, Meyer E, Stampanoni M, Carmeliet P, Emmert MY, Bozinov O, Regli L, Schwab ME, Vogel J, Hoerstrup SP. Nogo-A regulates vascular network architecture in the postnatal brain. J Cereb Blood Flow Metab. 2017 Feb;37(2):614-631. doi: 10.1177/0271678×16675182. Epub 2016 Nov 13. PubMed PMID: 27927704; PubMed Central PMCID: PMC5381465.

198: Stienen MN, Schaller K, Cock H, Lisnic V, Regli L, Thomson S. eLearning resources to supplement postgraduate neurosurgery training. Acta Neurochir (Wien). 2017 Feb;159(2):325-337. doi: 10.1007/s00701-016-3042-7. Epub 2016 Dec 5. PubMed PMID: 27921190.

199: Walker JH, Hackenberg A, Bozinov O, Berger C, Scheer I, Grotzer MA, Gerber NU. Ommaya reservoir “off-duty” causing major late-onset complications in a child with medulloblastoma. Pediatr Blood Cancer. 2017 Jun;64(6). doi: 10.1002/pbc.26384. Epub 2016 Dec 1. PubMed PMID: 27905687.

200: Giuliani ME, Hope A, Mangona V, Guckenberger M, Mantel F, Peulen H, Sonke JJ, Belderbos J, Werner-Wasik M, Ye H, Grills IS. Predictors and Patterns of Regional Recurrence Following Lung SBRT: A Report From the Elekta Lung Research Group. Clin Lung Cancer. 2017 Mar;18(2):162-168. doi: 10.1016/j.cllc.2016.10.006. Epub 2016 Oct 26. PubMed PMID: 27876604.

201: Takemoto M, Boissière L, Vital JM, Pellisé F, Perez-Grueso FJS, Kleinstück F, Acaroglu ER, Alanay A, Obeid I. Are sagittal spinopelvic radiographic parameters significantly associated with quality of life of adult spinal deformity patients? Multivariate linear regression analyses for pre-operative and short-term post-operative health-related quality of life. Eur Spine J. 2017 Aug;26(8):2176-2186. doi: 10.1007/s00586-016-4872-y. Epub 2016 Nov 18. PubMed PMID: 27864681.

202: Rieber J, Abbassi-Senger N, Adebahr S, Andratschke N, Blanck O, Duma M, Eble MJ, Ernst I, Flentje M, Gerum S, Hass P, Henkenberens C, Hildebrandt G, Imhoff D, Kahl H, Klass ND, Krempien R, Lohaus F, Lohr F, Petersen C, Schrade E, Streblow J, Uhlmann L, Wittig A, Sterzing F, Guckenberger M. Influence of Institutional Experience and Technological Advances on Outcome of Stereotactic Body Radiation Therapy for Oligometastatic Lung Disease. Int J Radiat Oncol Biol Phys. 2017 Jul 1;98(3):511-520. doi: 10.1016/j.ijrobp.2016.09.026. Epub 2016 Sep 26. PubMed PMID: 27843031.

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In 2013, Sarnthein et al., have installed a patient registry focused on cranial neurosurgery. Surgeries are characterized by indication, treatment, location and other specific neurosurgical parameters. Preoperative state and postoperative outcome are recorded prospectively using neurological and sociological scales. Complications are graded by their severity in a therapy-oriented complication score system (Clavien Dindo Grading system, CDG). Results are presented at the monthly clinical staff meeting.

Data acquisition compatible with the clinic workflow permitted to include all eligible patients into the registry. Until December 2015, they have registered 2880 patients that were treated in 3959 surgeries and 8528 consultations. Since the registry is fully operational (August 2014), they have registered 325 complications on 1341 patient discharge forms (24%). In 64% of these complications, no or only pharmacological treatment was required. At discharge, there was a clear correlation of the severity of the complication and the Karnofsky Performance Status (KPS, ρ = -0.3, slope -6 KPS percentage points per increment of CDG) and the length of stay (ρ = 0.4, slope 1.5 days per increment of CDG).

While the therapy-oriented complication scores correlate reasonably well with outcome and length of stay, they do not account for new deficits that cannot be treated. Outcome grading and complication severity grading thus serve a complimentary purpose. Overall, the registry serves to streamline and to complete information flow in the clinic, to identify complication rates and trends early for the internal quality monitoring and communication with patients. Conversely, the registry influences clinical practice in that it demands rigorous documentation and standard operating procedures ¹⁾.

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A population study of patients with glioma diagnosed between 1980 and 1994 in the Canton of Zurich in Switzerland confirmed the overall poor prognosis of glioblastoma. To explore changes in outcome, registry data were reevaluated for patients diagnosed between 2005 and 2009.

Patients with glioblastoma who were diagnosed between 2005 and 2009 were identified by the Zurich and Zug Cancer Registry. The prognostic significance of epidemiological and clinical data, isocitrate dehydrogenase 1 (IDH1)R132H mutation status, and O6 methylguanine DNA methyltransferase (MGMT) promoter methylation status was analyzed using the Kaplan-Meier method and the Cox proportional hazards model.

A total of 264 patients with glioblastoma were identified, for an annual incidence of 3.9 compared with the previous incidence of 3.7. The mean age of the patients at the time of diagnosis was 59.5 years in the current cohort compared with 61.3 years previously. The overall survival (OS) rate was 46.4% at 1 year, 22.5% at 2 years, and 14.4% at 3 years in the current study compared with 17.7% at 1 year, 3.3% at 2 years, and 1.2% at 3 years as reported previously. The median OS for all patients with glioblastoma was 11.5 months compared with 4.9 months in the former patient population. The median OS was 1.9 months for best supportive care, 6.2 months for radiotherapy alone, 6.7 months for temozolomide alone, and 17.0 months for radiotherapy plus temozolomide. Multivariate analysis revealed age, Karnofsky performance score, extent of tumor resection, first-line treatment, year of diagnosis, and MGMT promoter methylation status were associated with survival in patients with IDH1R132H -nonmutant glioblastoma.

The OS of patients newly diagnosed with glioblastoma in the Canton of Zurich in Switzerland markedly improved from 1980 through 1994 to 2005 through 2009. Cancer 2016. © 2016 American Cancer Society ²⁾.