Rosuvastatin
Rosuvastatin is a potent statin.
Biochemical, histopathological, ultrastructural analysis and functional tests revealed that rosuvastatin exhibits meaningful neuroprotection effects against spinal cord injury 1).
Rosuvastatin pretreatment ameliorates early brain injury (EBI) after a subarachnoid hemorrhage (SAH) through the attenuation of oxidative stress and nuclear factor-kappa B (NF-κB) mediated inflammation 2).
Both topical application and systemic administration of ROS show meaningful preventive effects over epidural fibrosis through multiple mechanisms. The results of a study provide the first experimental evidence of the preventive effects of ROS over epidural fibrosis 3)
Rosuvastatin promoted endothelialization of the coiled aneurysm neck via induction of endothelial progenitor cells (EPCs), suggesting that promoting endothelialization provides an additional therapeutic opportunity during vascular endothelium repair 4)