Pitavastatin has a suppressive effect on CA progression through the inhibition of NF-kappaB activation in aneurysmal walls. Moreover, pitavastatin treatment can cause the regression of degenerative changes in preexisting CA walls. Pitavastatin is a promising candidate for a novel preventive agent against subarachnoid hemorrhage 1).
1)
Aoki T, Kataoka H, Ishibashi R, Nakagami H, Nozaki K, Morishita R, Hashimoto
N. Pitavastatin suppresses formation and progression of cerebral aneurysms
through inhibition of the nuclear factor kappaB pathway. Neurosurgery. 2009
Feb;64(2):357-65; discussion 365-6. doi: 10.1227/01.NEU.0000336764.92606.1D.
PubMed PMID: 19190463.