Obstructive Hydrocephalus Etiology



Obstructive hydrocephalus typically is caused by a blockage in the normal circulation of CSF within the brain. This can be due to the scarring of a ventricle or a tumor. When the obstruction is due to a tumor, it is important to realize that the tumor has only a 10% chance for growth and the only treatment required is for the hydrocephalus.

In children with congenital malformations that do not allow CSF to flow properly, or In adults or children, when tumors or blood clots obstruct CSF circulation, or

As a result of injury or infection.

A study confirms the trend of the predominance of congenital causes of hydrocephalus in Africa, even if maternal infections can be involved in the development of some of them. The morbimortality of this pathology remains important, especially concerning neurocognitive outcomes 1)

Examples: Pineal germinoma.


Obstructive hydrocephalus secondary to enlarged Virchow Robin space (VRS) is a rare entity, with only a handful of cases reported in the literature. Presenting symptoms varies widely from headaches, through to dizziness.

Donaldson et al. report a 31 year old male who presents with pulsatile tinnitus and an MRI showing obstructive hydrocephalus secondary to tumefactive VRS. After a CSF diversion procedure in the form of an ETV he had almost complete resolution of his symptoms.

This is the first case of obstructive hydrocephalus secondary to enlarged Virchow-Robin spaces, presenting with pulsatile tinnitus 2).

Obstructive hydrocephalus from enlarged massa intermedia 3).

Large intracranial arachnoid cysts in locations compressing CSFpathways causing hydrocephalus are also candidates for surgical fenestration 4).


1)
Kpélao E, Ahanogbé KMH, Egu K, Doléagbénou AK, Moumouni AEK, Sossoukpe S, Ségbédji KK, Bakondé HE, Lawson D, Abaltou B, Abdoulaye HM, Békéti KA. Children hydrocephalus in Togo: etiologies, treatment, and outcomes. Surg Neurol Int. 2022 Dec 2;13:560. doi: 10.25259/SNI_927_2022. PMID: 36600766; PMCID: PMC9805628.
2)
Donaldson C, Chatha G, Chandra RV, Goldschlager T. Obstructive hydrocephalus secondary to enlarged Virchow-Robin spaces: A rare cause of pulsatile tinnitus. World Neurosurg. 2017 Mar 4. pii: S1878-8750(17)30292-9. doi: 10.1016/j.wneu.2017.02.119. [Epub ahead of print] PubMed PMID: 28268131.
3)
Vastani A, Al-Faiadh W, O Chieng D, Siddiqui A, Bleil C, Singh R, Zebian B. Obstructive hydrocephalus due to an enlarged massa intermedia treated with endoscopic third ventriculostomy. Br J Neurosurg. 2023 Jan 16:1-4. doi: 10.1080/02688697.2022.2159924. Epub ahead of print. PMID: 36647190.
4)
Beltagy MAE, Enayet AER. Surgical indications in pediatric arachnoid cysts. Childs Nerv Syst. 2022 Oct 26. doi: 10.1007/s00381-022-05709-y. Epub ahead of print. PMID: 36284010.
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