Myofibril
A myofibril (also known as a muscle fibril or sarcostyle) is a basic rod-like organelle of a muscle cell. Skeletal muscles are composed of long, tubular cells known as muscle fibers, and these cells contain many chains of myofibrils. Each myofibril has a diameter of 1–2 micrometers.
The upregulated genes in the ruptured cerebral arteriovenous malformation group are involved in inflammatory processes and extracellular matrix organization. Some of the downregulated genes participate in cell adhesion and myofibril assembly, indicating the role of enhanced inflammation and reduced inflammation vessel strength in ruptured cerebral arteriovenous malformation 1).
1)
Li H, Yan Z, Huo R, Ya X, Xu H, Liu Z, Jiao Y, Weng J, Wang J, Wang S, Cao Y. RNA sequencing analysis between ruptured and un-ruptured brain AVM. Chin Neurosurg J. 2022 Jun 2;8(1):13. doi: 10.1186/s41016-022-00282-4. PMID: 35655323.