Focal cortical dysplasia
Focal cortical dysplasia (FCD) was first described as a distinct neuropathological entity in 1971 by Taylor and colleagues. FCD is thought to be an embryological migration disorder and is thus considered a non-progressive, unchangeable disease throughout life 1).
Focal cortical dysplasia is a malformation of cortical development, which is the most common cause of drug resistant epilepsy in the pediatric population 2).
Epidemiology
Classification
Pathogenesis
Diagnosis
Treatment
Outcome
Case series
Case reports
1)
Kuroda N, Fujimoto A, Enoki H, Arai Y, Okanishi T. A case of focal cortical
dysplasia type Ib atypically showing reversible intensity changes on magnetic
resonance imaging which could be affected by epileptic discharge activity. Childs
Nerv Syst. 2019 Feb 27. doi: 10.1007/s00381-019-04093-4. [Epub ahead of print]
PubMed PMID: 30810857.
2)
Kabat J, Król P. Focal cortical dysplasia - review. Pol J Radiol. 2012
Apr;77(2):35-43. PubMed PMID: 22844307; PubMed Central PMCID: PMC3403799.