Epstein-Barr virus

Epstein-Barr virus 1) is associated with a broad spectrum of lymphoproliferative disorders, and is detectable in ≈ 30–50% of systemic lymphomas; however, it has been associated with almost 100% of Primary central nervous system lymphoma 2), especially AIDS-related cases 3).

Nasopharyngeal carcinomas: may be related to Epstein-Barr Virus (EBV) infection


1)
Hochberg FH, Miller G, Schooley RT, et al. Central- Nervous-System Lymphoma Related to Epstein-Barr Virus. N Engl J Med. 1983; 309:745–748
2)
MacMahon EME, Glass JD, Hayward SD, et al. Epstein-Barr Virus in AIDS-Related Primary Central Nervous System Lymphoma. Lancet. 1991; 338: 969–973
3)
Burger PC, Scheithauer BW, Vogel FS. Surgical Pathology of the Nervous System and Its Coverings. 4th ed. New York: Churchill Livingstone; 2002
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