Dual antiplatelet therapy complications
Dual antiplatelet therapy is associated with high early risks of major and gastrointestinal bleeding that decline after the first month in trial cohorts 1).
It is known that stent-assisted coiling (SAC) for ruptured wide-neck intracranial aneurysms has a good efficacy; however, there is an increased risk of perioperative hemorrhagic complications due to the need for dual antiplatelet therapy (DAPT). 2)
Ventriculoperitoneal shunt complication after dual antiplatelet therapy.
1)
Hilkens NA, Algra A, Kappelle LJ, Bath PM, Csiba L, Rothwell PM, Greving JP;
CAT Collaboration. Early time course of major bleeding on antiplatelet therapy
after TIA or ischemic stroke. Neurology. 2018 Jan 26. pii:
10.1212/WNL.0000000000004997. doi: 10.1212/WNL.0000000000004997. [Epub ahead of
print] PubMed PMID: 29374102.
2)
H. Roh, J. Kim, H. Bae, K. Chong, J.H. Kim, S.I. Suh, T.H. Kwon, W. Yoon,
Comparison of stent-assisted and no-stent coil embolization for safety and effectiveness in the treatment of ruptured intracranial aneurysms, J. Neurosurg.
(2019) 1–7