Antiplatelet therapy
Rationale for Antiplatelet Therapy
Endovascular treatments involve the placement of foreign materials (coils, stents, or flow diverters) that can trigger platelet aggregation and thrombus formation. Antiplatelet therapy mitigates this risk by inhibiting platelet activation and aggregation.
Dual Antiplatelet Therapy (DAPT): Standard regimen for stent-assisted coiling and flow diverter placement.
Single Antiplatelet Therapy (SAPT): Occasionally used for simple coiling procedures.
The use of antiplatelet therapy (including ASA, aspirin) for stroke prevention in AF is increasingly limited:
Although antiplatelet agents reduce the risk of stroke in patients with AF, they are less effective than anticoagulant therapy.
In the AVERROES study, apixaban was superior to ASA for stroke prevention and was associated with a similar rate of major bleeding