Adult spinal deformity surgery



Adult spinal deformity surgery is a specialized surgical procedure aimed at correcting abnormal curvatures and alignment of the spine in adults. These deformities can result from various conditions, including degenerative changes, scoliosis, kyphosis, or a combination of factors. The primary goals of adult spinal deformity surgery are to alleviate pain, improve spinal alignment, restore function, and enhance the patient's quality of life.

Before surgery, a comprehensive evaluation is conducted, including a detailed medical history, physical examination, imaging studies (such as X-rays, MRI, and CT scans), and assessment of pain, mobility, and neurological function. This evaluation helps determine the extent and nature of the deformity and guides treatment decisions.


Frailty-based prehabilitation for patients undergoing spinal deformity surgery 1)

Adult spinal deformity surgery is reserved for a small subset of patients who have failed all reasonable conservative (non-operative) measures. They generally have disabling back and/or leg pain and spinal imbalance. Their functional activities are severely restricted and their overall quality of life has been reduced substantially.

Sagittal spinopelvic alignment varies with age. Thus, operative realignment targets should account for age, with younger patients requiring more rigorous alignment objectives 2)


The goals of surgery are to restore spinal balance and reduce pain and discomfort by relieving pressure off the nerves (decompression) and maintaining corrected alignment by fusing and stabilizing the spinal segments. Surgical stabilization involves anchoring hooks, wires or screws to the spinal segments and using metal rods to link the anchors together. They act as a tether and allow the spine to fuse in the corrected position. Fusion is performed by using the patient’s own bone or using a cadaver or synthetic bone substitutes. In more severe cases, spinal segments have to be cut and realigned (osteotomy) or entire segments may have to be removed prior to realigning the spine (vertebral column resection). There are many different types of surgical procedures designed to treat adult spinal deformities. A detailed description of each is beyond the scope of this discussion.

It is important to note that surgery in the adult deformity population is riskier than in the adolescent teenager. The complication rate is significantly higher and the recovery is a lot slower. Therefore, surgery should only be undertaken as a last resort and only after the patient has a clear understanding of the risks and benefits. All reasonable non-surgical measures should be attempted first. At the same time, when patients are carefully chosen and are mentally well-prepared for the surgery, excellent functional outcomes can be obtained which at times can be a positive life-changing experience for a given individual patient.

Recent advances in surgical techniques include less invasive approaches by making smaller incisions as well as using biological substances to accelerate the fusion process. The use of computer-assisted navigation systems and various forms of the spinal cord and nerve monitoring may help in improving surgical precision and accuracy. Although promising, longer follow-ups are needed before one can conclude that they are superior to existing time-honored methods.

Adult spinal deformity surgery involves various surgical approaches, which may include:

Decompression: Removing pressure on spinal nerves or the spinal cord.

Fusion: Joining vertebrae together to stabilize the spine.

Osteotomies: Surgical cuts in the bone to correct deformities and restore proper alignment.

Instrumentation: The use of implants (such as screws, rods, and cages) to support and stabilize the spine.

Minimally invasive surgery for adult spinal deformity.

Minimally invasive surgery (MIS) is an alternative to open deformity surgery for the treatment of patients with adult spinal deformity. However, at this time MIS techniques are not as versatile as open deformity techniques, and MIS techniques have been reported to result in suboptimal sagittal plane correction or pseudarthrosis when used for severe deformities. The minimally invasive spinal deformity surgery (MISDEF) algorithm was created to provide a framework for rational decision making for surgeons who are considering MIS versus open spine surgery.

Methods: A team of experienced spinal deformity surgeons developed the MISDEF algorithm that incorporates a patient's preoperative radiographic parameters and leads to one of 3 general plans ranging from MIS direct or indirect decompression to open deformity surgery with osteotomies. The authors surveyed fellowship-trained spine surgeons experienced with spinal deformity surgery to validate the algorithm using a set of 20 cases to establish interobserver reliability. They then resurveyed the same surgeons 2 months later with the same cases presented in a different sequence to establish intraobserver reliability. Responses were collected and tabulated. Fleiss' analysis was performed using MATLAB software.

Results: Over a 3-month period, 11 surgeons completed the surveys. Responses for MISDEF algorithm case review demonstrated an interobserver kappa of 0.58 for the first round of surveys and an interobserver kappa of 0.69 for the second round of surveys, consistent with the substantial agreement. In at least 10 cases there was perfect agreement between the reviewing surgeons. The mean intraobserver kappa for the 2 surveys was 0.86 ± 0.15 (± SD) and ranged from 0.62 to 1.

The use of the MISDEF algorithm provides consistent and straightforward guidance for surgeons who are considering either an MIS or an open approach for the treatment of patients with adult spinal deformities. The MISDEF algorithm was found to have a substantial inter- and intraobserver agreement. Although further studies are needed, the application of this algorithm could provide a platform for surgeons to achieve the desired goals of surgery 3).

After surgery, patients undergo a period of recovery and rehabilitation. This may involve wearing a brace, physical therapy, and gradually returning to normal activities. The length of recovery can vary based on the complexity of the surgery and the patient's overall health.


Acute needs must be considered following Adult Spinal Deformity surgery, however, matched analysis comparing 30-day hospital readmissions, 90-day return to surgery, postoperative complications, and patient-reported outcomes demonstrated minimal benefit for NON, REHAB, or skilled nursing facility (SNF) versus HOME at 1-year and 2-year follow-up, questioning the risk and cost/benefits of routine use of non-home discharge 4).


1)
Iqbal J, Roy JM, Kazim SF, Bowers CA. Frailty-based prehabilitation for patients undergoing spinal deformity surgery. J Neurosurg Sci. 2023 Sep 18. doi: 10.23736/S0390-5616.23.06132-5. Epub ahead of print. PMID: 37721773.
2)
Lafage R, Schwab F, Challier V, Henry JK, Gum J, Smith J, Hostin R, Shaffrey C, Kim HJ, Ames C, Scheer J, Klineberg E, Bess S, Burton D, Lafage V; International Spine Study Group. Defining Spino-Pelvic Alignment Thresholds: Should Operative Goals in Adult Spinal Deformity Surgery Account for Age? Spine (Phila Pa 1976). 2016 Jan;41(1):62-8. doi: 10.1097/BRS.0000000000001171. PMID: 26689395.
3)
Mummaneni PV, Shaffrey CI, Lenke LG, Park P, Wang MY, La Marca F, Smith JS, Mundis GM Jr, Okonkwo DO, Moal B, Fessler RG, Anand N, Uribe JS, Kanter AS, Akbarnia B, Fu KM; Minimally Invasive Surgery Section of the International Spine Study Group. The minimally invasive spinal deformity surgery algorithm: a reproducible rational framework for decision making in minimally invasive spinal deformity surgery. Neurosurg Focus. 2014 May;36(5):E6. doi: 10.3171/2014.3.FOCUS1413. PMID: 24785488.
4)
Bess S, Line BG, Nunley P, Ames C, Burton D, Mundis G, Eastlack R, Hart R, Gupta M, Klineberg E, Kim HJ, Kelly M, Hostin R, Kebaish K, Lafage V, Lafage R, Schwab F, Shaffrey C, Smith JS; International Spine Study Group. Postoperative Discharge to Acute Rehabilitation or Skilled Nursing Facility Compared to Home Does Not Reduce Hospital Readmissions, Return to Surgery or Improve Outcomes Following Adult Spine Deformity Surgery. Spine (Phila Pa 1976). 2023 Sep 11. doi: 10.1097/BRS.0000000000004825. Epub ahead of print. PMID: 37694516.
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