Somatostatin receptors are receptors for the ligand somatostatin, a small neuropeptide associated with neural signaling, particularly in the post-synaptic response to NMDA receptor co-stimulation/activation. Somatostatin is encoded by a CRE and is very susceptible to gene promoter region activation by transcription factor CREB.
There are five known somatostatin receptors:
SST1 (SSTR1)
SST2 (SSTR2)
SST3 (SSTR3)
SST4 (SSTR4)
SST5 (SSTR5)