WHO grade 1 glioma refers to a type of brain tumor that is classified according to the World Health Organization (WHO) grading system. The WHO grading system categorizes brain tumors based on their histological features, which involve examining the tumor cells and the surrounding tissue under a microscope.

Grade 1 gliomas are the least aggressive and least malignant type of glioma. They are characterized by slow-growing tumor cells that closely resemble normal brain cells. Grade 1 gliomas are typically associated with a better prognosis compared to higher grade gliomas.

Common examples of WHO grade 1 gliomas include pilocytic astrocytoma and ganglioglioma. These tumors are usually well-defined, have a relatively low proliferation rate, and tend to occur in younger individuals. Grade 1 gliomas often have distinct clinical and radiological features that aid in diagnosis.

The treatment approach for WHO grade 1 gliomas may involve surgical resection (removal) of the tumor, depending on its location and size. In some cases, additional treatments such as radiation therapy or chemotherapy may be considered. Regular monitoring and follow-up with imaging studies, such as magnetic resonance imaging (MRI), are typically recommended to assess tumor progression and response to treatment.

It is important to note that medical knowledge and advancements continue to evolve, and new research may lead to changes in the understanding and management of WHO grade 1 gliomas