Nucleus of the thalamus.

Thalamic ventralis intermedius deep brain stimulation (VIM-DBS) is generally effective in treating refractory tremor in Parkinson's disease (PD) and in essential tremor (ET), but some patients do not respond well due to side effects or from loss of the effect of stimulation over time.

Gamma Knife thalamotomy GKT with a maximal dose of 130 Gy to the VIM is a safe procedure that can replace other surgical procedures ¹⁾.

A patient in whom 8.8 years following the implantation of a bilateral deep brain stimulation (DBS) into the Vim, a high grade glioma was diagnosed in close proximity to the two electrode leads. A possible relationship between the permanent DBS and the development of the brain tumour is discussed ²⁾.