Therapeutic Enthusiasm

Therapeutic enthusiasm refers to the premature or exaggerated optimism about the clinical potential of a treatment or molecular target, often based on limited, early-stage, or preclinical evidence.

🧪 In research contexts: It usually manifests when authors or scientists:

Overstate the translational relevance of a molecular finding

Propose therapeutic applications without sufficient validation in humans

Ignore biological complexity, safety, or feasibility

⚠️ Why it's problematic: Therapeutic enthusiasm can:

Mislead readers, funders, or clinicians

Fuel hype cycles that later collapse

Undermine scientific credibility when results fail to translate

In short: Therapeutic enthusiasm turns a petri dish into a miracle cure—on paper.