Selisistat

1: Jin P, Qi D, Cui Y, Lenahan C, Deng S, Tao X. Activation of LRP6 with HLY78 Attenuates Oxidative Stress and Neuronal Apoptosis via GSK3β/Sirt1/PGC-1α Pathway after ICH. Oxid Med Cell Longev. 2022 Apr 4;2022:7542468. doi: 10.1155/2022/7542468. PMID: 35419167; PMCID: PMC9001077.

2: Xia DY, Yuan JL, Jiang XC, Qi M, Lai NS, Wu LY, Zhang XS. SIRT1 Promotes M2 Microglia Polarization via Reducing ROS-Mediated NLRP3 Inflammasome Signaling After Subarachnoid Hemorrhage. Front Immunol. 2021 Nov 24;12:770744. doi: 10.3389/fimmu.2021.770744. PMID: 34899720; PMCID: PMC8653696.

3: Zhang XS, Lu Y, Li W, Tao T, Wang WH, Gao S, Zhou Y, Guo YT, Liu C, Zhuang Z, Hang CH, Li W. Cerebroprotection by dioscin after experimental subarachnoid haemorrhage via inhibiting NLRP3 inflammasome through SIRT1-dependent pathway. Br J Pharmacol. 2021 Sep;178(18):3648-3666. doi: 10.1111/bph.15507. Epub 2021 May 27. PMID: 33904167.

4: Xu W, Yan J, Ocak U, Lenahan C, Shao A, Tang J, Zhang J, Zhang JH. Melanocortin 1 receptor attenuates early brain injury following subarachnoid hemorrhage by controlling mitochondrial metabolism via AMPK/SIRT1/PGC-1α pathway in rats. Theranostics. 2021 Jan 1;11(2):522-539. doi: 10.7150/thno.49426. PMID: 33391490; PMCID: PMC7738864.

5: Zhang XS, Lu Y, Tao T, Wang H, Liu GJ, Liu XZ, Liu C, Xia DY, Hang CH, Li W. Fucoxanthin Mitigates Subarachnoid Hemorrhage-Induced Oxidative Damage via Sirtuin 1-Dependent Pathway. Mol Neurobiol. 2020 Dec;57(12):5286-5298. doi: 10.1007/s12035-020-02095-x. Epub 2020 Sep 2. PMID: 32876840.

6: Li W, Guo B, Tao K, Li F, Liu Z, Yao H, Feng D, Liu X. Inhibition of SIRT1 in hippocampal CA1 ameliorates PTSD-like behaviors in mice by protections of neuronal plasticity and serotonin homeostasis via NHLH2/MAO-A pathway. Biochem Biophys Res Commun. 2019 Oct 15;518(2):344-350. doi: 10.1016/j.bbrc.2019.08.060. Epub 2019 Aug 14. PMID: 31421827.

7: Yu LM, Dong X, Xue XD, Zhang J, Li Z, Wu HJ, Yang ZL, Yang Y, Wang HS. Protection of the myocardium against ischemia/reperfusion injury by punicalagin through an SIRT1-NRF-2-HO-1-dependent mechanism. Chem Biol Interact. 2019 Jun 1;306:152-162. doi: 10.1016/j.cbi.2019.05.003. Epub 2019 May 4. PMID: 31063767.

8: Chen G, Zhang B, Xu H, Sun Y, Shi Y, Luo Y, Jia H, Wang F. Suppression of Sirt1 sensitizes lung cancer cells to WEE1 inhibitor MK-1775-induced DNA damage and apoptosis. Oncogene. 2017 Dec 14;36(50):6863-6872. doi: 10.1038/onc.2017.297. Epub 2017 Sep 4. PMID: 28869605.

9: Wang D, Li Z, Zhang Y, Wang G, Wei M, Hu Y, Ma S, Jiang Y, Che N, Wang X, Yao J, Yin J. Targeting of microRNA-199a-5p protects against pilocarpine-induced status epilepticus and seizure damage via SIRT1-p53 cascade. Epilepsia. 2016 May;57(5):706-16. doi: 10.1111/epi.13348. Epub 2016 Mar 6. PMID: 26945677.

10: Yang Y, Jiang S, Dong Y, Fan C, Zhao L, Yang X, Li J, Di S, Yue L, Liang G, Reiter RJ, Qu Y. Melatonin prevents cell death and mitochondrial dysfunction via a SIRT1-dependent mechanism during ischemic-stroke in mice. J Pineal Res. 2015 Jan;58(1):61-70. doi: 10.1111/jpi.12193. Epub 2014 Dec 9. PMID: 25401748.