Rhino-Orbital-Cerebral Mucormycosis Treatment
1. Surgical Intervention
- Debridement: Aggressive removal of necrotic tissue.
- Orbital Exenteration: Required in severe cases to prevent intracranial spread.
2. Antifungal Therapy
- Liposomal Amphotericin B: First-line therapy (5–10 mg/kg/day).
- Step-Down Therapy: Posaconazole or Isavuconazole for long-term management.
3. Managing Underlying Conditions
- Tight control of blood glucose levels.
- Reduce or discontinue corticosteroids.
4. Supportive Care
- Oxygen therapy for hypoxia.
- Fluid and electrolyte management.