🎭 Radiogenomic Theater
Definition: A term used to describe the increasingly common practice of combining advanced imaging (radiomics) and genomic data to produce impressive-looking studies that promise clinical transformation — but deliver little beyond glossy figures, moderate AUCs, and speculative conclusions.
Characteristics:
- Overuse of deep learning models without external validation
- Ambiguous clinical endpoints masked by heatmaps and pipelines
- Conclusions inflated to justify grants or headlines
- Real-world applicability: close to zero
- Frequently published in journals chasing translational buzzwords
Translation: > *Science that performs better on posters than in practice. It looks like progress, sounds like innovation — but doesn’t change how we treat patients.*