Prophylactic antibiotics for skull base fracture

The routine use of prophylactic antibiotics is controversial. This remains true even in the presence of a CSF fistula; see CSF fistula (cranial).

However, most ENT physicians recommend treating fractures through the nasal sinuses as open contaminated fractures, and they use broad-spectrum antibiotics (e.g. ciprofloxacin) for 7–10 days.

If there is a Cerebrospinal fluid fistula pneumococcal vaccine is recommended for adults age 2–65 years

Prophylactic antibiotics for temporal bone fracture