prophylactic_antibiotics_for_cerebrospinal_fluid_fistula

Prophylactic antibiotics for cerebrospinal fluid fistula

Prophylactic antibiotics are controversial. There was no difference in the incidence of morbidity of meningitis between treated and untreated patients 1).

Furthermore, the risk of selecting resistant strains appears real 2) and is therefore usually avoided.

Prophylactic antibiotics for posttraumatic cerebrospinal fluid fistula

1)
Klastersky J, Sadeghi M, Brihaye J. Antimicrobial 2328 Prophylaxis in Patients with Rhinorrhea or Otorrhea: A Double Blind Study. Surg Neurol. 1976; 6:111–114
2)
Spetzler RF, Zabramski JM. Cerebrospinal Fluid Fistula. Contemp Neurosurg. 1986; 8:1–7
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