Primary central nervous system lymphoma chemotherapy
General information
For Primary central nervous system lymphoma:
In non-AIDS cases, chemotherapy combined with XRT prolongs survival compared to XRT alone. 1).
Methotrexate (MTX)
Rituximab
Rituximab is available since 1997 for the treatment of refractory systemic B-cell non-Hodgkin lymphoma. Intrathecally may be more effective for CD33 + lymphomas.
1)
DeAngelis LM, Yahalom J, Heinemann M-H, et al. Primary Central Nervous System Lymphomas: Combined Treatment with Chemotherapy and Radiotherapy. Neurology. 1990; 40:80–86