Stereotactic intervention into the posterior hypothalamus gives satisfactory results for controlling both aggressive, violent behavioral disorders and intractable pain. From the endocrinological point of view, this procedure activates the hypothalamic-hypophyseal axis only temporarily, without causing any serious dysfunctions 1).
see Posteromedial Hypothalamic Deep Brain Stimulation for Refractory Aggressiveness
1)
Mayanagi Y, Hori T, San K. The posteromedial hypothalamus and pain, behavior, with special reference to endocrinological findings. Appl Neurophysiol. 1978;41(1-4):223-31. doi: 10.1159/000102421. PMID: 365099.