Posterior inferior cerebellar artery aneurysm treatment

The vicinity of brainstem and cranial nerves as well as the limited operative working space make clip ligation of posterior inferior cerebellar artery (PICA) aneurysms challenging. The small caliber of the PICA and the broad neck often associated with these aneurysms also create challenges in preserving this artery during treatment. Few data exist to compare the 2 treatment approaches for aneurysms in this location 1).

Endovascular treatment is associated with higher risks of recurrence, requiring additional treatment. Outcomes were mostly impacted by clinical state at admission 2).

Owing to the evolution of endovascular interventions and devices and the higher rates of microsurgical complications, vertebral artery (VA) and posterior inferior cerebellar artery (PICA) aneurysms are predominantly treated with endovascular procedures 3) 4) 5) 6) 7) 8) 9)


1)
Bohnstedt BN, Ziemba-Davis M, Edwards G, Brom J, Payner TD, Leipzig TJ, Scott JA, DeNardo AJ, Palmer E, Cohen-Gadol AA. Treatment and outcomes among 102 posterior inferior cerebellar artery aneurysms: a comparison of endovascular and microsurgical clip ligation. World Neurosurg. 2015 May;83(5):784-93. doi: 10.1016/j.wneu.2014.12.035. Epub 2014 Dec 23. PubMed PMID: 25541085.
2)
Sejkorová A, Petr O, Mulino M, Cihlář J, Hejčl A, Thomé C, Sameš M, Lanzino G. Management of posterior inferior cerebellar artery aneurysms: What factors play the most important role in outcome? Acta Neurochir (Wien). 2017 Mar;159(3):549-558. doi: 10.1007/s00701-016-3058-z. Epub 2017 Jan 9. PubMed PMID: 28066873.
3)
Spetzler R.F., McDougall C.G., Zabramski J.M., et al. The barrow ruptured aneurysm trial: 6-year results. J Neurosurg. 2015;123(3):609–617.
4)
Catapano J.S., Ducruet A.F., Cadigan M.S., et al. Endovascular treatment of vertebral artery dissecting aneurysms: a 20-year institutional experience. J Neurointerventional Surg. 2022;14(3):257–261.
5)
Aboukaïs R., Zairi F., Boustia F., Bourgeois P., Leclerc X., Lejeune J.P. Vertebral artery-posterior inferior cerebellar artery convergence aneurysms treated by endovascular or surgical treatment: mid- and long-term outcome. Neurochirurgie. 2016;62(2):72–77.
6)
Awad A.J., Mascitelli J.R., Haroun R.R., De Leacy R.A., Fifi J.T., Mocco J. Endovascular management of fusiform aneurysms in the posterior circulation: the era of flow diversion. Neurosurg Focus. 2017;42(6):E14.
7)
Eller J.L., Dumont T.M., Mokin M., et al. Endovascular treatment of posterior circulation aneurysms. Neurol Res. 2014;36(4):339–343.
8)
Starnoni D., Maduri R., Al Taha K., et al. Ruptured PICA aneurysms: presentation and treatment outcomes compared to other posterior circulation aneurysms. A Swiss SOS study. Acta Neurochir. 2019;161(7):1325–1334.
9)
Ali A.M.S., Hannan C.J., Islim A.I., Mascitelli J.R., Javadpour M. Surgical and endovascular treatment of saccular posterior inferior cerebellar artery aneurysms: systematic review and meta-analysis. World Neurosurg. 2022;162:e168–e177.
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