Platelet-activating factor
Platelet-activating factor, also known as PAF, PAF-acether or AGEPC (acetyl-glyceryl-ether-phosphorylcholine), is a potent phospholipid activator and mediator of many leukocyte functions, platelet aggregation and degranulation, inflammation, and anaphylaxis. It is also involved in changes to vascular permeability, the oxidative burst, chemotaxis of leukocytes, as well as augmentation of arachidonic acid metabolism in phagocytes.
Ginseng (Panax ginseng) has antiplatelet activity through thromboxane inhibition and platelet-activating factor 1).
Some authors also advocate cautious use of ginger and vitamin E when planning a surgery, but the exact antiplatelet mechanism is unclear 2).