Peridural scar

Although peridural scar tissue is frequently blamed for causing recurrent symptoms, 1) 2) there has been no proof of a correlation between the two 3).

Peridural fibrosis is an inevitable sequela to lumbar disc surgery just as post-op fibrosis is a consequence of any surgical procedure. Even patients who are relieved of their pain following discectomy develop some scar tissue post-op 4).

Although it has been shown that if a patient has recurrent radicular pain following a lumbar discectomy there is a 70% chance that extensive peridural scar will be found on MRI 5), this study also showed that on post-op MRIs at 6 months, 43% of patients will have extensive scar, but 84% of the time this will be asymptomatic 6). Thus, one must use clinical grounds to determine if a patient with an extensive scar on MRI is in the 16% minority of patients with radicular symptoms attributable to scar.


Postoperative epidural fibrosis (PEF) localized around the exposed dura and nerve roots is a known radiologic entity seen after lumbar spine surgery. Although excessive PEF is associated with residual and new lumbar pain and radiculopathy, its role as the generator of the pain is still discussed. Various materials acting as an adhesion barrier have been tested. There is no undebated class I evidence that any one of them is suitable to reduce or avoid PEF and provide a better clinical outcome.

Dural fibrosis and epidural adhesion after laminectomy are developed from adjacent dense scar tissue, which is a natural wound healing process 7) 8) 9) 10). , and ranked as the major contributor for postoperative pain recurrence after laminectomy or discectomy, and has been implicated as an important cause of failed back surgery syndrome.

The epidural hyperplasia can extend to the spinal canal and adhere to the dura and nerve root, which lead to the periodic recurrent symptoms including radicular pain 11) 12) 13) 14) 15).

At the same time, dural fibrosis made the risk of nerve root injury, dural laceration and Iatrogenic injury greatly improved, which challenging doctors for exploring the operation technology 16) 17) 18).

Although the epidural scar tissue adhesion can be removed and the adhered nerve root can also be released, but this need second operation 19) 20) 21).

A reoperation on the scar can produce more scarring 22) 23).

Epiduroscopic laser neural decompression (ELND) provides a new view of the epidural space as well as an alternative treatment for a herniated disc and epidural fibrosis.


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21)
Kim SB, Lee KW, Lee JH, Kim MA, An BW. The effect of hyaluronidase in interlaminar lumbar epidural injection for failed back surgery syndrome. Ann Rehabil Med. 2012;36:466–473.
22)
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