Percept

The Medtronic Percept™ PC is a cutting-edge, implantable neurostimulator designed for deep brain stimulation (DBS) therapy. It stands out as the first commercially available DBS system equipped with BrainSense™ technology, enabling clinicians to record and interpret brain signals in real time while delivering therapeutic stimulation.

🔍 Key Features

1. BrainSense™ Technology Real-time sensing: Captures local field potentials (LFPs) from implanted leads, providing insights into the patient's neural activity.

Personalized therapy: Allows clinicians to correlate brain signals with patient-reported symptoms, facilitating tailored adjustments to stimulation settings.

2. Adaptive DBS (aDBS) Capability Closed-loop stimulation: Automatically adjusts stimulation parameters based on detected neural biomarkers, aiming to optimize symptom control throughout the day and night.

Enhanced symptom management: Particularly beneficial for Parkinson's disease patients experiencing motor fluctuations, as it adapts to their changing needs.

3. Directional Stimulation with SenSight™ Leads Precise targeting: Utilizes segmented leads to direct electrical stimulation more accurately, potentially reducing side effects and improving efficacy.

Sensing-enabled leads: Combines directional stimulation with the ability to record neural signals, enhancing the adaptability of the therapy.

4. Recharge-Free Design Long-lasting battery: Offers a projected battery life exceeding five years, eliminating the need for regular recharging and reducing maintenance for patients.

Smart battery technology: Provides real-time estimates of remaining battery life, assisting in timely planning for device replacement.

5. MRI Compatibility Full-body MRI access: Approved for both 1.5T and 3T MRI scans under specified conditions, allowing patients to undergo necessary imaging without discontinuing therapy.

6. User-Friendly Patient Programmer

Intuitive interface: Patients can monitor battery status, adjust stimulation settings within prescribed parameters, and log events such as medication intake or symptom occurrences.

Enhanced communication: Facilitates better patient-clinician interactions by providing detailed therapy usage data.

🧠 Clinical Applications

The Percept™ PC neurostimulator is indicated for the treatment of several neurological conditions, including:

Parkinson's disease

Essential tremor

Dystonia

Epilepsy

Obsessive-compulsive disorder (OCD)

It's important to note that for certain conditions like dystonia and OCD, the device is designated as a Humanitarian Use Device, and its effectiveness for these indications has not been established.

📈 Clinical Impact

The integration of BrainSense™ technology and adaptive stimulation positions the Percept™ PC as a significant advancement in DBS therapy. By enabling real-time monitoring and adjustment of stimulation based on neural activity, it offers a more personalized and responsive treatment approach, potentially improving outcomes for patients with movement disorders and other neurological conditions.

For more detailed information, you can visit Medtronic's official page on the Percept™ PC Neurostimulator: Medtronic Percept™ PC Neurostimulator.