Pallidal Deep Brain Stimulation indications

Pallidal Deep Brain Stimulation for Parkinson’s Disease

see also Subthalamic deep brain stimulation for Parkinson's disease

GPi and subthalamic nucleus (STN) DBS improve motor function and activities of daily living for Parkinson's disease (PD) patients. Differences in therapeutic efficacy for PD were not observed between the 2 procedures. STN DBS allowed greater reduction in medication for patients, whereas GPi DBS provided greater relief from psychiatric symptoms. An understanding of other symptomatic aspects of targeting each region and long-term observations on therapeutic effects are needed 1).


1)
Liu Y, Li W, Tan C, Liu X, Wang X, Gui Y, Qin L, Deng F, Hu C, Chen L. Meta-analysis comparing deep brain stimulation of the globus pallidus and subthalamic nucleus to treat advanced Parkinson's disease. J Neurosurg. 2014 Sep;121(3):709-18. doi: 10.3171/2014.4.JNS131711. Epub 2014 Jun 6. PubMed PMID: 24905564.
  • pallidal_deep_brain_stimulation_indications.txt
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