Neurosurgical Guidelines



Tewarie et al. aim to offer a critical approach to the ethical and legal status of guidelines in neurosurgery. To this aim, the authors discuss: 1) the current state of neurosurgical guidelines and the evidence they are based on; 2) the degree of implementation of these guidelines; 3) the legal status of guidelines in medical disciplinary cases; and 4) the ethical balance between confident and critical use of guidelines. Ultimately, guidelines are neither laws that should always be followed nor purely academic efforts with little practical use. Every patient is unique, and tailored treatment defined by the surgeon will ensure optimal care; guidelines play an important role in creating a solid base that can be adhered to or deviated from, depending on the situation. From a research perspective, it is inevitable to rely on weaker evidence initially in order to generate more robust evidence later, and clinician-researchers have an ethical duty to contribute to generating and improving neurosurgical guidelines 1)


Anaesthetic and peri-operative management for thrombectomy procedures in stroke patients


Anterior cervical discectomy and fusion versus posterior decompression in patients with degenerative cervical myelopathy: a systematic review and meta-analysis


Comparison of Clinical Efficacy of Transforaminal and Interlaminar Epidural Steroid Injection in Radicular Pain due to Cervical Diseases: A Systematic Review and Meta-analysis


Decompression alone versus decompression with instrumented fusion in the treatment of lumbar degenerative spondylolisthesis: a systematic review and meta-analysis of randomised trials


Deep Brain Stimulation for Obsessive-Compulsive Disorder Guideline.


Evidence-based guideline for the prevention and management of perioperative infection


Gastric cancer intracranial metastases guidelines


Iatrogenic Pseudomeningocele Guidelines


Occipital Neuralgia Guideline


Parent perceptions and decision making about treatments for epilepsy: a qualitative evidence synthesis


Severe traumatic brain injury guidelines


Spontaneous Intracerebral Hemorrhage Guideline


Surgical and clinical efficacy of minimally invasive sacroiliac joint fusion surgery: a meta-analysis protocol


Systematic Review and Meta-Analysis of Randomized Controlled Trials for Scalp Block in Craniotomy


Unruptured Cerebral Aneurysm Guidline

The analysis of surgical processes should be a standard of health systems.

Valero et al., describe the circuit of care and postoperative treatment for neurosurgical interventions in the centres of Spain.

From June to October 2014, a survey dealing with perioperative treatments and postoperative circuits after neurosurgical procedures was sent to the chiefs of Anaesthesiology of 73 Spanish hospitals with neurosurgery and members of the Neuroscience Section of SEDAR.

They obtained 45 responses from 30 centres (41.09%). Sixty percent of anaesthesiologists perform preventive locoregional analgesic treatment. Pain intensity is systematically assessed by 78%. Paracetamol, non-steroidal anti-inflammatory and morphine combinations are the most commonly used. A percentage of 51.1 are aware of the incidence of postoperative nausea after craniotomy and 86.7% consider multimodal prophylaxis to be necessary. Dexamethasone is given as antiemetic (88.9%) and/or anti-oedema treatment (68.9%). A percentage of 44.4 of anaesthesiologists routinely administer anticonvulsive prophylaxis in patients with supratentorial tumours (levetiracetam, 88.9%), and 73.3% of anaesthesiologists have postoperative surveillance protocols. The anaesthesiologist (73.3%) decides the patient's destination, which is usually ICU (83.3%) or PACU (50%). Postoperative neurological monitoring varied according to the type of intervention, although strength and sensitivity were explored in between 70-80%.

There is great variability in the responses, probably attributable to the absence of guidelines, different structures and hospital equipment, type of surgery and qualified personnel. We need consensual protocols to standardize the treatment and the degree of monitoring needed during the postoperative period 3).

Major pharmaceutical companies selling antihypertensive drug products in the Japanese market had a significant financial connection with the JSH2019 authors. Financial relationships between pharmaceutical companies and authors or Japanese medical societies are raising significant concerns about the credibility of clinical guidelines and the potentially biases and undue influences that they may cause, especially with respect to adverse prescription patterns 4).


1)
Tewarie IA, Hulsbergen AFC, Volovici V, Broekman MLD. The ethical and legal status of neurosurgical guidelines: the neurosurgeon's golden fleece or Achilles' heel? Neurosurg Focus. 2020 Nov;49(5):E14. doi: 10.3171/2020.8.FOCUS20597. PMID: 33130626.
2)
Tunkel AR, Hasbun R, Bhimraj A, et al. 2017 Infectious Diseases Society of America's Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis. Clin Infect Dis. 2017;64(6):e34-e65. doi:10.1093/cid/ciw861
3)
Valero R, Carrero E, Fàbregas N, Iturri F, Saiz-Sapena N, Valencia L; Sección de Neurociencia de la Sociedad Española de Anestesiología y Reanimación.. National survey on postoperative care and treatment circuits in neurosurgery. Rev Esp Anestesiol Reanim. 2017 Mar 16. pii: S0034-9356(17)30027-0. doi: 10.1016/j.redar.2017.01.003. [Epub ahead of print] English, Spanish. PubMed PMID: 28318531.
4)
Senoo Y, Saito H, Ozaki A, Sawano T, Shimada Y, Yamamoto K, Suzuki Y, Tanimoto T. Pharmaceutical company payments to authors of the Japanese guidelines for the management of hypertension. Medicine (Baltimore). 2021 Mar 26;100(12):e24816. doi: 10.1097/MD.0000000000024816. PMID: 33761642.
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