Neurolysis
The first report of chemical neurolysis was made in 1863 by Luton who delivered irritant chemicals subcutaneously in patients with sciatica, offering them significant alleviation of pain 1).
In cases of ulnar nerve compression at the cubital tunnel, both neurolysis and transposition are effective in improving clinical outcome. The only statistically significant advantage of neurolysis over transposition seems to be relief of localized elbow pain. Kamat et al, recommend neurolysis as the preferred procedure 2).
1)
Luton A, generales de medecin, 1863
2)
Kamat AS, Jay SM, Benoiton LA, Correia JA, Woon K. Comparative outcomes of
ulnar nerve transposition versus neurolysis in patients with entrapment
neuropathy at the cubital tunnel: a 20-year analysis. Acta Neurochir (Wien). 2014
Jan;156(1):153-7. doi: 10.1007/s00701-013-1962-z. Epub 2013 Dec 3. PubMed PMID:
24292808.