Mild Degenerative Cervical Myelopathy

Khosravi et al. included studies with Mild degenerative Cervical Myelopathy which was defined as a modified Japanese Orthopaedic Association scale score of 15 to 17 or a Japanese Orthopaedic Association scale score of 13 to 16. Independent reviewers screened all the records, and discrepancies between the reviewers were solved in a session with the senior author. For risk of bias assessment, RoB 2 tool was used for randomized clinical trials and ROBINS-I for non-randomized studies.

After screening 6 087 manuscripts, only 8 studies met the inclusion criteria. Lower pre-operative mJOA scores and quality-of-life measurement scores were reported by multiple studies to predict better surgical outcomes compared to other groups. Pre-operative Increased signal intensity magnetic resonance imaging on T2 weighted image of the cervical spinal cord was also reported to predict poor outcomes. Neck pain before intervention resulted in improved patient-reported outcomes. Two studies also reported motor symptoms prior to surgery as outcome predictors.

Lower quality of life before surgery, neck pain, lower pre-operative mJOA scores, motor symptoms before surgery, female gender, gastrointestinal comorbidities, surgical procedure and surgeon's experience with specific techniques, and high signal intensity of cord in T2 MRI were the surgical outcome predictors reported in the literature. Lower Quality of Life (QoL) score and neck prior to surgery were reported as predictors of the more improved outcome, but increased signal intensity magnetic resonance imaging on T2 weighted image of the cervical spinal cord was reported as an unfavorable outcome predictor ¹⁾