Microparticle

see Extracellular vesicle

Microparticles (MP) are small vesicular micro-molecules released by red and white blood cells, platelets and endothelial cells that can change rapidly and specifically depending on the type of cellular insult. They may serve as useful tools to target a specific pool of proteins associated with the development of cerebral vasospasm (CV) post aSAH.

These and other proteins may be useful as reliable biomarkers to guide in stratifying patients into categories of risk to develop cerebral vasospasm (CV) post aSAH. These results will deepen our understanding of the mechanisms of cerebral vasospasm and potentially facilitate the development of safer and more effective therapies therapies for cerebral vasospasm ¹⁾