Medulloblastoma Radiographic Features
Medulloblastoma Classification presents many faces in medical imaging.
Location is the key to this approach
cerebellar peduncle/foramen of Luschka
very likely Medulloblastoma, WNT-activated and therefore best prognosis
very likely SHH subgroup and therefore intermediate prognosis likely desmoplastic/nodular/medulloblastoma with extensive nodularity (MBEN)
midline
may be Group 3 medulloblastoma, Group 4 medulloblastoma or Medulloblastoma, SHH-activated
typically infants with a tumor with ill-defined margins but prominent enhancement: likely Group 3 medulloblastoma or Medulloblastoma, SHH-activated and therefore worst prognosis
typically children with a tumor with well-defined margins but mild or no enhancement: likely Group 4 medulloblastoma and therefore slightly better prognosis
adults with variably defined and variably enhancing tumors: most likely Medulloblastoma, SHH-activated; hemorrhage raises the probability of group 1)