Sir Geoffrey Jefferson FRS (1886–1961) was a British neurologist and pioneering neurosurgeon. He was educated in Manchester, England, obtaining his medical degree in 1909. He became a fellow of the Royal College of Surgeons two years later. He married in 1914, and moved to Canada. On the outbreak of World War I, he returned to Europe and worked at the Anglo-Russian Hospital in Petrograd, Russia, and then with the Royal Army Medical Corps in France.

After the war, he returned to Manchester, working at the Salford Royal NHS Foundation Trust. It was here, in 1925 that Jefferson performed the first successful embolectomy in England. By 1934, he was a neurosurgeon at the Manchester Royal Infirmary, becoming the UK's first professor of neurosurgery at the University of Manchester five years later.