lumbar_degenerative_spondylolisthesis_magnetic_resonance_imaging

Lumbar degenerative spondylolisthesis magnetic resonance imaging

Several studies have reported that disc degeneration and signs of facet effusion detected on T2 weighted image- MRI can be indicators of potential lumbar spine instability 1) 2). However, qualitative MRI evaluations are highly dependent on the subjective judgments of the radiologist. In a study, quantitative value assessments including disc height, facet fluid thickness, ligamentum flavum thickness, and disk signal intensity on T1 weighted image (T1W) and T2W MRI was assessed to identify potential factors and their efficacy in the diagnosis of unstable L4/L5 degenerative spondylolisthesis. A quantitative study of lumbar MRI measurements was conducted to identify predisposing factors indicative of spinal instability in patients with L4/L5 LDS. In total, 81 patients [58 patients in the stable group (SG) and 23 patients in the unstable group (UG)] who were diagnosed with L4/L5 LDS on X-ray and MRI between January 2021 and January 2022 were included in this study. Disk height, disk signal intensity on T1-weighted (T1W) and T2-weighted (T2W) images, facet joint fluid thickness, and ligamentum flavum thickness was measured on MRI, and the differences in these parameters between the two groups were evaluated. The receiver operating characteristic curve was generated, and the area under the curve (AUC), cut-off value, sensitivity (Se), specificity (Sp), positive predictive value (PPV), and negative predictive value (NPV) were calculated for parameters found to be significantly different between the two groups. The facet joint fluid was significantly thicker in the UG than in the SG (P<0.01), and a cut-off value of 1.45 mm was found to have an AUC of 0.77 and an SE, SP, PPV, and NPV of 73.9, 67.2, 69.3, and 69.77%, respectively. No significant differences were identified between the two groups for mean disk height, ligamentum flavum thickness, or disk signal intensity on T1W or T2W images. The facet joint fluid thickness on axial T2W images may represent a useful predictor of spinal instability in patients with LDS. Therefore, spinal instability should be assessed, and additional evaluation methods, such as standing lateral flexion-extension radiographs, should be performed when facet fluid is detected on lumbar MRI 3).

Grade 1 lumbar spondylolisthesis L4 over L5 anterolisthesis with bilateral L5 spondylolysis. At the L4-L5 level, signs of marked multifactorial vertebral lumbar spinal stenosis are observed due to posteromedial protrusion of the intervertebral disc, facet hypertrophy, and yellow ligaments. Posteromedial protrusions at practically all levels studied (from T10-D11 to L4-5) with signs of mild lumbar spinal stenosis at L2-L3 and lumbar foraminal stenosis at left D11-D12, D12-L1, L1-L2, L2-L3, L3-L4 bilateral. The L1/L2 disc also presents a posteromedial extrusion component migrated caudally. Minimal crush fracture of the L5 vertebral body of subacute-chronic chronology and benign etiology with minimal loss of vertebral body height with minimal bone marrow edema at the present time. Left convexity lumbar scoliosis and lumbar hyperlordosis. Signs of disc degeneration and dehydration of thoracolumbar discs.


1)
Kuhns BD, Kouk S, Buchanan C, Lubelski D, Alvin MD, Benzel EC, Mroz TE and Tozzi J: Sensitivity of magnetic resonance imaging in the diagnosis of mobile and nonmobile L4-L5 degenerative spondylolisthesis. Spine J. 15:1956–1962. 2015
2)
Cho IY, Park SY, Park JH, Suh SW and Lee SH: MRI findings of lumbar spine instability in degenerative spondylolisthesis. J Orthop Surg (Hong Kong). 25(2309499017718907)2017.
3)
Hung ND, Duc NM, Hang NT, Anh NH, Minh ND, Hue ND. The efficacy of quantitative magnetic resonance imaging in the diagnosis of unstable L4/L5 degenerative spondylolisthesis. Biomed Rep. 2022 Jun 8;17(2):67. doi: 10.3892/br.2022.1550. PMID: 35815186; PMCID: PMC9260153.
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