Intracranial teratoma magnetic resonance imaging


Primary intracranial teratomas are usually localized in the pineal and the suprasellar regions, and often present an ovoid or lobulated mass with or without multilocularity on MRI. Marked enhancement of the solid portion or the thick wall of the tumor was the key feature for distinguishing mature teratoma and malignant teratoma 1)


MRI has advantages in characterizing the shape, texture, outline, composition, and original position of the tumor, as well as its association with surrounding structures, particularly in enhanced scanning. MRI can identify the original position of the tumor and its invasiveness and subsequently guide surgery 2).

hyperintense components due to fat and proteinaceous/lipid-rich fluid

intermediate components of soft tissue

hypointense components due to calcification and blood products

solid soft tissue components show enhancement

Again mixed signal from differing components.


Nevertheless, MR imaging does not allow differentiation of germinomas from other NGGCTs 3) 4).


1)
Liu Z, Lv X, Wang W, An J, Duan F, Feng X, Chen X, Ouyang B, Li S, Singh S, Qiu S. Imaging characteristics of primary intracranial teratoma. Acta Radiol. 2014 Sep;55(7):874-81. doi: 10.1177/0284185113507824. Epub 2013 Oct 8. PMID: 24103916.
3)
Liang L, Korogi Y, Sugahara T, et al. MRI of intracranial germ-cell tumours. Neuroradiology 2002;44(5):382–388.
4)
Douglas-Akinwande AC, Ying J, Momin Z, Mourad A, Hattab EM. Diffusion-weighted imaging characteristics of primary central nervous system germinoma with histopathologic correlation: a retrospective study. Acad Radiol 2009;16(11):1356–1365
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