Intracranial hemangioblastoma

Outcomes After Stereotactic Radiosurgery for Intracranial Hemangioblastoma in Von Hippel-Lindau Disease and Sporadic Cases: An International Multicenter Study
A case of recurrent hemangioblastoma receiving blood supply from the mastoid and transosseous branches of the occipital artery
Fatal intracranial haemorrhage shortly after belzutifan initiation in von Hippel-Lindau (VHL) disease-associated haemangioblastoma
Neurological Outcome of Spinal Hemangioblastomas: An International Observational Multicenter Study About 35 Surgical Cases
Belzutifan for von Hippel-Lindau disease-associated renal cell carcinoma and other neoplasms (LITESPARK-004): 50 months follow-up from a single-arm, phase 2 study
Immunohistochemical Expression of PAX8 in Central Nervous System Hemangioblastomas: A Potential Diagnostic Pitfall for Neuropathologists
Retinal capillary hemangioma in a pthisical globe: Late sequelae in a case of Von Hippel-Lindau (VHL) disease presenting with endophthalmitis
Hemangioblastoma

Intracranial hemangioblastoma is a World Health Organization (WHO) grade I tumor of the CNS composed of capillary-sized blood vessels and stromal cells with variable lipid content. It can occur sporadically or in association with von Hippel-Lindau (VHL) disease.

Location: Most often posterior fossa (especially cerebellum).

Histology: Highly vascular with stromal cells, often with foamy cytoplasm.

Clinical presentation: Depends on size and location; may include headache, ataxia, visual disturbances, or signs of increased intracranial pressure due to cyst formation or mass effect.

Radiology: Cystic lesion with an enhancing mural nodule on contrast MRI is characteristic.

Management: Surgical resection is the treatment of choice; stereotactic radiosurgery is an option for select cases.

Prognosis: Excellent for sporadic lesions after complete resection; more complex in VHL-associated cases due to multiplicity.

see Intracranial hemangioblastoma classification.

see Intracranial hemangioblastoma treatment.