Interstitial brachytherapy in neurosurgery

• Innovations in intraoperative therapies in neurosurgical oncology: a narrative review
• Multidisciplinary management strategies for recurrent brain metastasis after prior radiotherapy: An overview
• Stereotactic body radiotherapy using CyberKnife versus interstitial brachytherapy in accelerated partial breast irradiation on left-sided breast: A comparison of dosimetric characteristics and preliminary clinical results
• Development and promotion of a 3D-printed phantom model for ultrasound-guided caudal block followed by intracavitary/interstitial brachytherapy for gynecological cancer
• Embryonal tumor with multilayered rosettes located in the brainstem: Promising results after multimodal treatment including interstitial brachytherapy
• Research progress in separation surgery combined with stereotactic radiotherapy of spinal metastases
• The occurrence and development of radiation-induced lung injury after interstitial brachytherapy and stereotactic radiotherapy in SD rats
• Boost modalities in cervical cancer: dosimetric comparison between intracavitary BT vs. intracavitary + interstitial BT vs. SBRT

A technique whereby radioactive implants are used to deliver locally high doses of radiation directly to tumors while exposing the nearby normal brain to less toxic doses. At present, the numbers are too small and the follow-up too short to determine the efficacy of interstitial brachytherapy ¹⁾.

Interstitial brachytherapy (IB) may reduce the rate of tumor growth, but it rarely produces clinical improvement. Patients are generally not considered for IB unless their Karnofsky performance score is ≥ 70.