High-grade glioma epidemiology
High-grade gliomas (HGGs) constitute the most common and aggressive primary brain tumor
High-grade gliomas are the most common primary malignant brain tumor in adults 1) 2) 3).
The top three most common sites for high-grade gliomas in the central nervous system involve the frontal lobe (25.9%), the temporal lobe (19.8%), and other brain areas (19.4%) 4).
They represent a widely heterogeneous group of tumors, the most frequent of which is glioblastoma.
see Glioblastoma epidemiology.
Its annual incidence has risen over the last decades, particularly amongst elderly people.
Approximately 89,000 new primary brain tumors are diagnosed in the United States each year, for which 27% are gliomas and 32.8% are malignant gliomas 5).