Hair-On-End

“Hair-On-End” appearance in the skull

1. common

a) congenital hemolytic anemia(e.g.thalassemia,sickle cell,hereditary spherocytosis,pyruvate kinase deficiency)

2. uncommon

a) hemangioma

b) cyanotic congenital heart disease (with secondary polycythemia)

c) iron deficiency anemia

d) metastases: especially neuroblastoma, thyroid carcinoma

e) multiple myeloma

f) meningioma

g) osteosarcoma

h) polycythemia vera