While endoluminal flow diverters function from within the parent artery by providing a scaffold for endothelial cell growth at the aneurysm neck and induction of intra-aneurysmal thrombosis 1) endosaccular devices mimic the endoluminal devices but within the aneurysmal sac itself. 2).
Several endosaccular flow disruptors have been developed, including the Woven EndoBridge (WEB; Microvention, Aliso Viejo, California), which was introduced in Europe in 2011, and Medina (Medtronic, Dublin, Ireland), Artisse (formerly LUNA; Medtronic) 3) 4)
1)
Kadirvel R, Ding YH, Dai D, Rezek I, Lewis DA, Kallmes DF. Cellular
mechanisms of aneurysm occlusion after treatment with a flow diverter. Radiology.
2014;270(2):394-399.
2)
Ding YH, Lewis DA, Kadirvel R, Dai D, Kallmes DF. The Woven EndoBridge:
a new aneurysm occlusion device. AJNR Am J Neuroradiol. 2011;32(3):607-611.
3)
Munich, SA, Chen, M. Endovascular advances in the treatment of cerebral
aneurysms: an overview of the development of new neuroendovascular techniques
and technology for the treatment of cerebral aneurysms. Endovasc Today.
2017;2(16):66-70.
4)
Rajah G, Narayanan S, Rangel-Castilla L. Update on flow diverters for the
endovascular management of cerebral aneurysms. Neurosurg Focus. 2017;42(6):E2.