Epoprostenol
Administration of the prostacyclin analogue epoprostenol significantly decreased C-reactive protein (CRP) and, to some extent, IL-6 levels in patients with severe traumatic brain injury TBI compared to placebo and indicate an interesting option for treatment of TBI and warrants future larger studies 1)
1)
Wahlström MR, Olivecrona M, Ahlm C, Bengtsson A, Koskinen LO, Naredi S, Hultin
M. Effects of prostacyclin on the early inflammatory response in patients with
traumatic brain injury-a randomised clinical study. Springerplus. 2014 Feb
18;3:98. doi: 10.1186/2193-1801-3-98. eCollection 2014. PubMed PMID: 24600548.