Dopamine agonist for Lactotroph adenoma
Lactotroph adenoma is the only type of pituitary tumor for which medical therapy (Dopamine agonists) may be the primary treatment in certain cases.
Dopamine agonists such as bromocriptine and cabergoline have been found to be an effective treatment for hyperprolactinemia, not only inducing adenoma shrinkage but also lowering serum prolactin levels. Among known dopamine agonists, cabergoline is the drug of choice due to its enhanced tolerability compared with bromocriptine 1).
1)
Krysiak R, Okopien B. Different Effects of Cabergoline and Bromocriptine on
Metabolic and Cardiovascular Risk Factors in Patients with Elevated Prolactin
Levels. Basic Clin Pharmacol Toxicol. 2014 Aug 13. doi: 10.1111/bcpt.12307. [Epub
ahead of print] PubMed PMID: 25123447.