Colchicine

Conflicting evidence shows either some 1) or no 2) therapeutic benefit for acute low back pain. Side effects of N/V and diarrhea were common 3).


1)
Meek JB, Giudice VW, McFadden JW, et al. Colchicine Confirmed as Highly Effective in Disk Disorders. Final Results of a Double-Blind Study. J Neuro & Orthop Med & Surg. 1985; 6:211–218
2)
Schnebel BE, Simmons JW. The Use of Oral Colchicine for Low-Back Pain. A Double-Blind Study. Spine. 1988; 13:354–357
3)
Bigos S, Bowyer O, Braen G, et al. Acute Low Back Problems in Adults. Clinical Practice Guideline No.14. AHCPR Publication No. 95-0642. Rockville, MD: Agency for Health Care Policy and Research, Public Health Service, U.S. Department of Health and Human Services; 1994
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