Circumscribed astrocytic gliomas
The World Health Organization Classification of Tumors of the Central Nervous System 2021, also known as WHO 5th edition, introduces substantial changes, especially within the glioma category, and separates adult-type and pediatric-type glial tumors into different categories for the first time. In addition, another category of glial tumors, “Circumscribed Astrocytic Gliomas” was also created. This group includes pilocytic astrocytoma, pleomorphic xanthoastrocytoma, subependymal giant cell astrocytoma, chordoid glioma, astroblastoma, and the highly nebulous novel entity high-grade astrocytoma with piloid features 1).
High-grade astrocytoma with piloid features
1)
Köy Y, Tihan T. Circumscribed astrocytic gliomas: Contribution of molecular analyses to histopathology diagnosis in the WHO CNS5 classification. Indian J Pathol Microbiol. 2022 May;65(Supplement):S33-S41. doi: 10.4103/ijpm.ijpm_1019_21. PMID: 35562132.