Chemical Thrombolysis

The most commonly used clot-busting drugs – also known as thrombolytic agents – include:

Eminase (anistreplase)

Retavase (reteplase)

Streptase (streptokinase, kabikinase)

t-PA (class of drugs that includes Activase)

TNKase (tenecteplase)

Abbokinase, Kinlytic (rokinase)

Thrombolysis is the breakdown (lysis) of blood clots by pharmacological means, and commonly called clot busting. It works by stimulating secondary fibrinolysis by plasmin through infusion of analogs of tissue plasminogen activator (tPA), the protein that normally activates plasmin.

see Acute ischemic stroke thrombolysis.

see Intraventricular thrombolysis.

Fibrinolytic Therapy Improves Outcomes in Patients with Epidural Hematomas Following Cranioplasty: A Pilot Study ¹⁾.