Charles University and Motol University Hospital

Department of Neurosurgery, 2nd Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu 84, 150 06 Prague 5, Czech Republic.

Tomas Cesak

David Netuka

To assess microsurgical and diagnostic cerebral angiography modules and their corresponding objective assessment scales as educational tools for European neurosurgical residents at the European Association of Neurosurgical Societies Resident Vascular Neurosurgery course, which was held in Prague, Czech Republic, on September 2013. Microsurgical skills and cerebral angiography are fundamental skills in vascular neurosurgery. There is a need to develop a simulation-based curriculum focusing on these skills for neurosurgical trainees worldwide.

The course consisted of 2 modules: microanastomosis and diagnostic cerebral angiography. In addition to an initial screening survey, each module was divided into 3 components: 1) a before didactic cognitive knowledge and technical skills testing, 2) a didactic lecture, and 3) an after didactic cognitive knowledge and technical skills testing. We compared the trainees' cognitive and technical scores from the before and after testing phases. Wilcoxon sum rank test was used to test statistical significance.

The knowledge test median scores increased from 63% and 68% to 80% and 88% (P < 0.01) on the microanastomosis and cerebral angiography modules, respectively. The practical hands-on simulation assessment median scores increased from 42% and 50% to 50.5% and 68% (P < 0.01) on the microanastomosis and cerebral angiography modules, respectively.

Our course suggests that a simulation-based vascular neurosurgery curriculum is feasible and may enhance resident knowledge and technical proficiency ¹⁾.

Prague Neurosurgical Week was an event in Prague, Czech Republic on August 29th – September 2nd, 2018.

The Neurosurgical Week started with the meeting of World Academy of Neurological Surgery, a members only conference which will bring top quality faculty from the next two combined events. The International Meningioma Society holded its annual conference along with the 13th International Conference on Cerebrovascular Surgery oustide of Asia for the first time. The two main conferences enjoyed the presence of WANS members and a unique combination of joint plenary sessions with targeted breakfast seminars and dedicated afternoon sessions. In general, the topics will be meningiomas, skull base, and cerebrovascular. The Week finished with a hands-on course on endoscopic neurosurgery organised by the WFNS Neurosurgical Anatomy Committee.

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2: Hrdlicka M, Kudr M, Krsek P, Tichy M, Kyncl M, Zamecnik J, Mohaplova M, Dudova I. Recovery from Autism after Successful Surgery for a Benign Brain Tumor Associated with Epilepsy. J Autism Dev Disord. 2019 Feb 19. doi: 10.1007/s10803-019-03935-z. [Epub ahead of print] PubMed PMID: 30783900.

3: Zapotocky M, Beera K, Adamski J, Laperierre N, Guger S, Janzen L, Lassaletta A, Figueiredo Nobre L, Bartels U, Tabori U, Hawkins C, Urbach S, Tsang DS, Dirks PB, Taylor MD, Bouffet E, Mabbott DJ, Ramaswamy V. Survival and functional outcomes of molecularly defined childhood posterior fossa ependymoma: Cure at a cost. Cancer. 2019 Feb 15. doi: 10.1002/cncr.31995. [Epub ahead of print] PubMed PMID: 30768777.

4: Kazda T, Misove A, Burkon P, Pospisil P, Hynkova L, Selingerova I, Dziacky A, Belanova R, Bulik M, Rehak Z, Poprach A, Slama O, Slampa P, Slaby O, Jancalek R, Lakomy R. Incidence of Hippocampal Metastases: Laterality and Implications for Unilateral Hippocampal Avoiding Whole Brain Radiotherapy. Biomed Res Int. 2018 Dec 13;2018:2459608. doi: 10.1155/2018/2459608. eCollection 2018. PubMed PMID: 30643795; PubMed Central PMCID: PMC6311293.

5: Liby P, Lomachinsky V, Felici G, Vaculik M, Krasnicanova H, Tichy M. Sagittal craniosynostosis associated with midline cephalhematoma or vice versa, case report and a review of the literature. Childs Nerv Syst. 2018 Dec 11. doi: 10.1007/s00381-018-4020-6. [Epub ahead of print] PubMed PMID: 30539297.

6: Tsang DS, Murray L, Ramaswamy V, Zapotocky M, Tabori U, Bartels U, Huang A, Dirks PB, Taylor MD, Hawkins C, Bouffet E, Laperriere N. Craniospinal irradiation as part of re-irradiation for children with recurrent intracranial ependymoma. Neuro Oncol. 2018 Nov 19. doi: 10.1093/neuonc/noy191. [Epub ahead of print] PubMed PMID: 30452715.

7: Ono T, Wagenaar J, Giorgi FS, Fabera P, Hanaya R, Jefferys J, Moyer JT, Harte-Hargrove LC, Galanopoulou AS. A companion to the preclinical common data elements and case report forms for rodent EEG studies. A report of the TASK3 EEG Working Group of the ILAE/AES Joint Translational Task Force. Epilepsia Open. 2018 Sep 24;3(Suppl Suppl 1):90-103. doi: 10.1002/epi4.12260. eCollection 2018 Nov. PubMed PMID: 30450486; PubMed Central PMCID: PMC6210053.

8: Štulík J, Nesnídal P, Kozelnická K, Barna M. [Surgical Treatment of High-Grade High-Dysplastic Spondylolistheses in Young Patients - Prospective Monocentric Study of 29 Patients]. Acta Chir Orthop Traumatol Cech. 2018;85(5):305-318. Czech. PubMed PMID: 30383526.

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12: Hejčl A, Růžička J, Proks V, Macková H, Kubinová Š, Tukmachev D, Cihlář J, Horák D, Jendelová P. Dynamics of tissue ingrowth in SIKVAV-modified highly superporous PHEMA scaffolds with oriented pores after bridging a spinal cord transection. J Mater Sci Mater Med. 2018 Jun 25;29(7):89. doi: 10.1007/s10856-018-6100-2. PubMed PMID: 29938301.

13: Baud MO, Perneger T, Rácz A, Pensel MC, Elger C, Rydenhag B, Malmgren K, Cross JH, McKenna G, Tisdall M, Lamberink HJ, Rheims S, Ryvlin P, Isnard J, Mauguière F, Arzimanoglou A, Akkol S, Deniz K, Ozkara C, Lossius M, Rektor I, Kälviäinen R, Vanhatalo LM, Dimova P, Minkin K, Staack AM, Steinhoff BJ, Kalina A, Krsek P, Marusic P, Jordan Z, Fabo D, Carrette E, Boon P, Rocka S, Mameniškienė R, Vulliemoz S, Pittau F, Braun KPJ, Seeck M. European trends in epilepsy surgery. Neurology. 2018 Jul 10;91(2):e96-e106. doi: 10.1212/WNL.0000000000005776. Epub 2018 Jun 13. PubMed PMID: 29898967.

14: Liby P, Torres VL, Taborsky J, Kyncl M, Tichy M. Electromagnetic navigation-guided neuroendoscopic transfrontal transaqueductal fenestration of expansive posterior fossa arachnoid cyst with simultaneous endoscopic third ventriculostomy in an infant. Childs Nerv Syst. 2018 Nov;34(11):2309-2312. doi: 10.1007/s00381-018-3847-1. Epub 2018 May 30. PubMed PMID: 29846773.

15: Waszak SM, Northcott PA, Buchhalter I, Robinson GW, Sutter C, Groebner S, Grund KB, Brugières L, Jones DTW, Pajtler KW, Morrissy AS, Kool M, Sturm D, Chavez L, Ernst A, Brabetz S, Hain M, Zichner T, Segura-Wang M, Weischenfeldt J, Rausch T, Mardin BR, Zhou X, Baciu C, Lawerenz C, Chan JA, Varlet P, Guerrini-Rousseau L, Fults DW, Grajkowska W, Hauser P, Jabado N, Ra YS, Zitterbart K, Shringarpure SS, De La Vega FM, Bustamante CD, Ng HK, Perry A, MacDonald TJ, Hernáiz Driever P, Bendel AE, Bowers DC, McCowage G, Chintagumpala MM, Cohn R, Hassall T, Fleischhack G, Eggen T, Wesenberg F, Feychting M, Lannering B, Schüz J, Johansen C, Andersen TV, Röösli M, Kuehni CE, Grotzer M, Kjaerheim K, Monoranu CM, Archer TC, Duke E, Pomeroy SL, Shelagh R, Frank S, Sumerauer D, Scheurlen W, Ryzhova MV, Milde T, Kratz CP, Samuel D, Zhang J, Solomon DA, Marra M, Eils R, Bartram CR, von Hoff K, Rutkowski S, Ramaswamy V, Gilbertson RJ, Korshunov A, Taylor MD, Lichter P, Malkin D, Gajjar A, Korbel JO, Pfister SM. Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort. Lancet Oncol. 2018 Jun;19(6):785-798. doi: 10.1016/S1470-2045(18)30242-0. Epub 2018 May 9. PubMed PMID: 29753700; PubMed Central PMCID: PMC5984248.

16: Liby P. In Reply: The Wolf Sign. Neurosurgery. 2018 May 1;82(5):E139. doi: 10.1093/neuros/nyy006. PubMed PMID: 29481614.

17: Garzia L, Kijima N, Morrissy AS, De Antonellis P, Guerreiro-Stucklin A, Holgado BL, Wu X, Wang X, Parsons M, Zayne K, Manno A, Kuzan-Fischer C, Nor C, Donovan LK, Liu J, Qin L, Garancher A, Liu KW, Mansouri S, Luu B, Thompson YY, Ramaswamy V, Peacock J, Farooq H, Skowron P, Shih DJH, Li A, Ensan S, Robbins CS, Cybulsky M, Mitra S, Ma Y, Moore R, Mungall A, Cho YJ, Weiss WA, Chan JA, Hawkins CE, Massimino M, Jabado N, Zapotocky M, Sumerauer D, Bouffet E, Dirks P, Tabori U, Sorensen PHB, Brastianos PK, Aldape K, Jones SJM, Marra MA, Woodgett JR, Wechsler-Reya RJ, Fults DW, Taylor MD. A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases. Cell. 2018 Feb 22;172(5):1050-1062.e14. doi: 10.1016/j.cell.2018.01.038. Erratum in: Cell. 2018 May 31;173(6):1549. PubMed PMID: 29474906; PubMed Central PMCID: PMC6346737.

18: Völker M, Fiederer LDJ, Berberich S, Hammer J, Behncke J, Kršek P, Tomášek M, Marusič P, Reinacher PC, Coenen VA, Helias M, Schulze-Bonhage A, Burgard W, Ball T. The dynamics of error processing in the human brain as reflected by high-gamma activity in noninvasive and intracranial EEG. Neuroimage. 2018 Jun;173:564-579. doi: 10.1016/j.neuroimage.2018.01.059. Epub 2018 Feb 20. PubMed PMID: 29471099.

19: Zapotocky M, Mata-Mbemba D, Sumerauer D, Liby P, Lassaletta A, Zamecnik J, Krskova L, Kyncl M, Stary J, Laughlin S, Arnoldo A, Hawkins C, Tabori U, Taylor MD, Bouffet E, Raybaud C, Ramaswamy V. Differential patterns of metastatic dissemination across medulloblastoma subgroups. J Neurosurg Pediatr. 2018 Feb;21(2):145-152. doi: 10.3171/2017.8.PEDS17264. Epub 2017 Dec 8. PubMed PMID: 29219788.

20: Blumcke I, Spreafico R, Haaker G, Coras R, Kobow K, Bien CG, Pfäfflin M, Elger C, Widman G, Schramm J, Becker A, Braun KP, Leijten F, Baayen JC, Aronica E, Chassoux F, Hamer H, Stefan H, Rössler K, Thom M, Walker MC, Sisodiya SM, Duncan JS, McEvoy AW, Pieper T, Holthausen H, Kudernatsch M, Meencke HJ, Kahane P, Schulze-Bonhage A, Zentner J, Heiland DH, Urbach H, Steinhoff BJ, Bast T, Tassi L, Lo Russo G, Özkara C, Oz B, Krsek P, Vogelgesang S, Runge U, Lerche H, Weber Y, Honavar M, Pimentel J, Arzimanoglou A, Ulate-Campos A, Noachtar S, Hartl E, Schijns O, Guerrini R, Barba C, Jacques TS, Cross JH, Feucht M, Mühlebner A, Grunwald T, Trinka E, Winkler PA, Gil-Nagel A, Toledano Delgado R, Mayer T, Lutz M, Zountsas B, Garganis K, Rosenow F, Hermsen A, von Oertzen TJ, Diepgen TL, Avanzini G; EEBB Consortium. Histopathological Findings in Brain Tissue Obtained during Epilepsy Surgery. N Engl J Med. 2017 Oct 26;377(17):1648-1656. doi: 10.1056/NEJMoa1703784. PubMed PMID: 29069555.

21: Plzák J, Kratochvil V, Kešner A, Šurda P, Vlasák A, Zvěřina E. Endoscopic endonasal approach for mass resection of the pterygopalatine fossa. Clinics (Sao Paulo). 2017 Oct;72(9):554-561. doi: 10.6061/clinics/2017(09)06. PubMed PMID: 29069259; PubMed Central PMCID: PMC5629706.

22: Maillard LG, Tassi L, Bartolomei F, Catenoix H, Dubeau F, Szurhaj W, Kahane P, Nica A, Marusic P, Mindruta I, Chassoux F, Ramantani G. Stereoelectroencephalography and surgical outcome in polymicrogyria-related epilepsy: A multicentric study. Ann Neurol. 2017 Nov;82(5):781-794. doi: 10.1002/ana.25081. Epub 2017 Nov 11. PubMed PMID: 29059488.

23: Liby P. Letter: The Wolf Sign. Neurosurgery. 2017 Nov 1;81(5):E68-E69. doi: 10.1093/neuros/nyx460. PubMed PMID: 28945905.

24: Beniczky S, Aurlien H, Brøgger JC, Hirsch LJ, Schomer DL, Trinka E, Pressler RM, Wennberg R, Visser GH, Eisermann M, Diehl B, Lesser RP, Kaplan PW, Nguyen The Tich S, Lee JW, Martins-da-Silva A, Stefan H, Neufeld M, Rubboli G, Fabricius M, Gardella E, Terney D, Meritam P, Eichele T, Asano E, Cox F, van Emde Boas W, Mameniskiene R, Marusic P, Zárubová J, Schmitt FC, Rosén I, Fuglsang-Frederiksen A, Ikeda A, MacDonald DB, Terada K, Ugawa Y, Zhou D, Herman ST. Standardized computer-based organized reporting of EEG: SCORE - Second version. Clin Neurophysiol. 2017 Nov;128(11):2334-2346. doi: 10.1016/j.clinph.2017.07.418. Epub 2017 Aug 9. Review. PubMed PMID: 28838815.

25: Liby P, Zamecnik J, Kyncl M, Zackova J, Tichy M. Electromagnetic navigation-guided neuroendoscopic removal of radiation-induced intraforniceal cavernoma as a late complication of medulloblastoma treatment. Childs Nerv Syst. 2017 Nov;33(11):2051-2055. doi: 10.1007/s00381-017-3519-6. Epub 2017 Jul 8. PubMed PMID: 28689346.

26: Engelborghs S, Niemantsverdriet E, Struyfs H, Blennow K, Brouns R, Comabella M, Dujmovic I, van der Flier W, Frölich L, Galimberti D, Gnanapavan S, Hemmer B, Hoff E, Hort J, Iacobaeus E, Ingelsson M, Jan de Jong F, Jonsson M, Khalil M, Kuhle J, Lleó A, de Mendonça A, Molinuevo JL, Nagels G, Paquet C, Parnetti L, Roks G, Rosa-Neto P, Scheltens P, Skårsgard C, Stomrud E, Tumani H, Visser PJ, Wallin A, Winblad B, Zetterberg H, Duits F, Teunissen CE. Consensus guidelines for lumbar puncture in patients with neurological diseases. Alzheimers Dement (Amst). 2017 May 18;8:111-126. doi: 10.1016/j.dadm.2017.04.007. eCollection 2017. PubMed PMID: 28603768; PubMed Central PMCID: PMC5454085.

27: Hrbáč T, Netuka D, Beneš V, Nosáľ V, Kešnerová P, Tomek A, Fadrná T, Beneš V Jr, Fiedler J, Přibáň V, Brozman M, Langová K, Herzig R, Školoudík D. SONOlysis in prevention of Brain InfaRctions During Internal carotid Endarterectomy (SONOBIRDIE) trial - study protocol for a randomized controlled trial. Trials. 2017 Jan 17;18(1):25. doi: 10.1186/s13063-016-1754-x. PubMed PMID: 28095924; PubMed Central PMCID: PMC5240392.

28: Vogt VL, Äikiä M, Del Barrio A, Boon P, Borbély C, Bran E, Braun K, Carette E, Clark M, Cross JH, Dimova P, Fabo D, Foroglou N, Francione S, Gersamia A, Gil-Nagel A, Guekht A, Harrison S, Hecimovic H, Heminghyt E, Hirsch E, Javurkova A, Kälviäinen R, Kavan N, Kelemen A, Kimiskidis VK, Kirschner M, Kleitz C, Kobulashvili T, Kosmidis MH, Kurtish SY, Lesourd M, Ljunggren S, Lossius MI, Malmgren K, Mameniskiené R, Martin-Sanfilippo P, Marusic P, Miatton M, Özkara Ç, Pelle F, Rubboli G, Rudebeck S, Ryvlin P, van Schooneveld M, Schmid E, Schmidt PM, Seeck M, Steinhoff BJ, Shavel-Jessop S, Tarta-Arsene O, Trinka E, Viggedal G, Wendling AS, Witt JA, Helmstaedter C; E-PILEPSY consortium. Current standards of neuropsychological assessment in epilepsy surgery centers across Europe. Epilepsia. 2017 Mar;58(3):343-355. doi: 10.1111/epi.13646. Epub 2017 Jan 9. PubMed PMID: 28067423.

29: Carreño M, Bien CG, Asadi-Pooya AA, Sperling M, Marusic P, Elisak M, Pimentel J, Wehner T, Mohanraj R, Uranga J, Gómez-Ibáñez A, Villanueva V, Gil F, Donaire A, Bargalló N, Rumià J, Roldán P, Setoain X, Pintor L, Boget T, Bailles E, Falip M, Aparicio J, Dalmau J, Graus F. Epilepsy surgery in drug resistant temporal lobe epilepsy associated with neuronal antibodies. Epilepsy Res. 2017 Jan;129:101-105. doi: 10.1016/j.eplepsyres.2016.12.010. Epub 2016 Dec 15. PubMed PMID: 28043058; PubMed Central PMCID: PMC5285301.

30: Liby P, Zamecnik J, Kyncl M, Tichy M. An olfactory groove schwannoma with a pseudocyst compressing the basal ganglia, internal capsule and optic tracts. Childs Nerv Syst. 2016 Nov;32(11):2269-2273. Epub 2016 Jun 21. PubMed PMID: 27325302.

31: Jayakar P, Gotman J, Harvey AS, Palmini A, Tassi L, Schomer D, Dubeau F, Bartolomei F, Yu A, Kršek P, Velis D, Kahane P. Diagnostic utility of invasive EEG for epilepsy surgery: Indications, modalities, and techniques. Epilepsia. 2016 Nov;57(11):1735-1747. doi: 10.1111/epi.13515. Epub 2016 Sep 28. PubMed PMID: 27677490.

32: Mühlebner A, van Scheppingen J, Hulshof HM, Scholl T, Iyer AM, Anink JJ, van den Ouweland AM, Nellist MD, Jansen FE, Spliet WG, Krsek P, Benova B, Zamecnik J, Crino PB, Prayer D, Czech T, Wöhrer A, Rahimi J, Höftberger R, Hainfellner JA, Feucht M, Aronica E. Novel Histopathological Patterns in Cortical Tubers of Epilepsy Surgery Patients with Tuberous Sclerosis Complex. PLoS One. 2016 Jun 13;11(6):e0157396. doi: 10.1371/journal.pone.0157396. eCollection 2016. PubMed PMID: 27295297; PubMed Central PMCID: PMC4905625.

33: Benova B, Krsek P, Sumnik Z, Kudr M, Komarek V, Tichy M. Initial manifestation of type I diabetes mellitus as an unusual cause of early post-operative seizures. Epileptic Disord. 2016 Jun 1;18(2):211-5. doi: 10.1684/epd.2016.0827. PubMed PMID: 27267220.

34: Kobulashvili T, Höfler J, Dobesberger J, Ernst F, Ryvlin P, Cross JH, Braun K, Dimova P, Francione S, Hecimovic H, Helmstaedter C, Kimiskidis VK, Lossius MI, Malmgren K, Marusic P, Steinhoff BJ, Boon P, Craiu D, Delanty N, Fabo D, Gil-Nagel A, Guekht A, Hirsch E, Kalviainen R, Mameniskiené R, Özkara Ç, Seeck M, Rubboli G, Krsek P, Rheims S, Trinka E. Current practices in long-term video-EEG monitoring services: A survey among partners of the E-PILEPSY pilot network of reference for refractory epilepsy and epilepsy surgery. Seizure. 2016 May;38:38-45. doi: 10.1016/j.seizure.2016.03.009. Epub 2016 Apr 1. PubMed PMID: 27104922.

35: Mühlebner A, Iyer AM, van Scheppingen J, Anink JJ, Jansen FE, Veersema TJ, Braun KP, Spliet WG, van Hecke W, Söylemezoğlu F, Feucht M, Krsek P, Zamecnik J, Bien CG, Polster T, Coras R, Blümcke I, Aronica E. Specific pattern of maturation and differentiation in the formation of cortical tubers in tuberous sclerosis omplex (TSC): evidence from layer-specific marker expression. J Neurodev Disord. 2016 Apr 1;8:9. doi: 10.1186/s11689-016-9142-0. eCollection 2016. PubMed PMID: 27042238; PubMed Central PMCID: PMC4818922.

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