Cerebrovascular atherosclerotic stenosis

The frequent occurrence of calcification in intracranial artery stenosis increases the risk of ischemic stroke


Cerebrovascular atherosclerotic stenosis (CAS) and intracranial aneurysm (IA) have a common underlying arterial pathology and common risk factors, but the clinical significance of CAS in IA rupture (IAR) is unclear. A study of Feng et al. aimed to investigate the effect of CAS on the risk of IAR.

They observed substantial differences in the severity of atherosclerotic stenosis, parent-artery stenosis, number of stenotic arteries, and intracranial/extracranial stenosis as indicators between ruptured and unruptured aneurysms. CAS is significantly associated with the risk of intracranial aneurysm rupture, whether in patients aged ≥65 years or <65 years. These findings indicate the clinical significance of CAS in IAR 1).


Basilar artery stenosis.

Carotid artery stenosis


1)
Feng X, Qi P, Wang L, Lu J, Wang HF, Wang J, Hu S, Wang D. Relationship between cerebrovascular atherosclerotic stenosis and rupture risk of unruptured intracranial aneurysm: A single-center retrospective study. Clin Neurol Neurosurg. 2019 Oct 1;186:105543. doi: 10.1016/j.clineuro.2019.105543. [Epub ahead of print] PubMed PMID: 31627063.
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