Cerebellar phaeohyphomycosis
Symptoms of cerebellar phaeohyphomycosis can include headache, nausea, vomiting, fever, altered mental status, and neurological deficits such as ataxia (loss of coordination), weakness, or paralysis.
Diagnosis often involves imaging studies such as MRI or CT scans to identify lesions in the cerebellum, followed by biopsy or culture to confirm the presence of fungal infection.
Treatment typically involves a combination of antifungal medications such as voriconazole, posaconazole, or amphotericin B, along with surgical intervention to remove infected tissue if feasible. Prognosis can vary depending on the extent of the infection, the immune status of the patient, and the timeliness of treatment.
Due to its rarity and potentially serious consequences, cerebellar phaeohyphomycosis requires prompt recognition and management by a multidisciplinary medical team, often including infectious disease specialists, neurosurgeons, and critical care physicians 1).