C57BL/6 (WT) Mice
C57BL/6 mice (commonly known as Black 6) are the most widely used inbred mouse strain in biomedical research.
Key Characteristics
- 🧬 Inbred strain – genetically homogeneous
- 🐭 Black fur, calm behavior
- 🔬 Common background for genetically engineered models
What does WT mean?
- WT stands for Wild-Type
- Mice that do not carry any gene modifications
- Serve as control group in experimental research
Scientific Uses
- Baseline for knockout/knock-in comparisons (e.g., AQP3⁻/⁻)
- Immunology, neurology, oncology, and metabolism studies
- Extensive availability and reference data