In a study, Nakamura et al. encountered a case of C11orf-RelA fusion-positive ST anaplastic ependymoma that was diagnosed in first tumor resection surgery of multi-staged gross total resection with molecular evidence. In ependymomas, regardless of tumor location or pathological grade, subtotal resection is associated with higher rates of mortality compared with GTR 1).
1)
Nakamura T, Fukuoka K, Ikeda J, Yoshitomi M, Udaka N, Tanoshima R, Tateishi K,
Yamanaka S, Ichimura K, Yamamoto T. Encouraging option of multi-staged gross
total resection for a C11orf-RelA fusion-positive supratentorial anaplastic
ependymoma. Brain Tumor Pathol. 2017 Oct;34(4):160-164. doi:
10.1007/s10014-017-0297-5. Epub 2017 Aug 22. PubMed PMID: 28831588.